SCHEMBL181890

SCHEMBL181890

Brc1ccc2c(c1)[nH]c1cc(Br)ccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.52
PDPK1 O15530 1/20 0.50
JAK2 O60674 1/20 0.50
PIM3 Q86V86 1/20 0.49
CHUK O15111 1/20 0.48
CYP2A6 P11509 2/20 0.45
AHR P35869 2/20 0.44
CCNB2 O95067 2/20 0.43
CDK1 P06493 2/20 0.43
CCNB1 P14635 2/20 0.43
CDK5 Q00535 2/20 0.43
CDK5R1 Q15078 2/20 0.43
CCNB3 Q8WWL7 2/20 0.43
GSK3A P49840 1/20 0.43
GSK3B P49841 1/20 0.43
CCNT1 O60563 1/20 0.43
CCNE2 O96020 1/20 0.43
CDK4 P11802 1/20 0.43
EIF2AK2 P19525 1/20 0.43
CCNA2 P20248 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29397381 1.00 METAP2 (0.52) METAP2PDPK1JAK2PIM3CHUK
SCHEMBL28272924 1.00 METAP2 (0.52) METAP2PDPK1JAK2PIM3CHUK
Ethane SCHEMBL29122859 0.95 METAP2 (0.48) METAP2PDPK1JAK2PIM3CHUK
SCHEMBL10050070 0.93 CHUK (0.48) METAP2PDPK1JAK2PIM3CHUK
SCHEMBL16552984 0.91 CHUK (0.61) METAP2PDPK1JAK2PIM3CHUK
SCHEMBL29764121 0.91 CHUK (0.61) METAP2PDPK1JAK2PIM3CHUK
SCHEMBL30286037 0.89 AHR (0.64) AHRCCNB2CDK1CCNB1CDK5
SCHEMBL29814236 0.89 AHR (0.64) AHRCCNB2CDK1CCNB1CDK5
SCHEMBL25294 0.89 AHR (0.64) AHRCCNB2CDK1CCNB1CDK5
SCHEMBL7251703 0.87 ALOX15 (0.48) METAP2PDPK1JAK2PIM3CHUK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 715 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118303347-A Method for testing toxicity of polyhalocarbazole as environmental pollutant by using zebra fish 浙江工业大学 2024-07-09 CN claimed
CN-118243812-A Method for measuring carbazole compounds in aquatic products based on internal standard method 舟山市食品药品检验检测研究院(国家海洋食品质量监督检验中心、浙江省海洋水产品质量检测中心、舟山市医疗器械质量监督检验所、舟山市药品不良反应监测中心、舟山市渔业检验检测中心、舟山市农产品质量检测中心) 2024-06-25 CN claimed
CN-116425764-B Triazine and carbazole-containing heat-activated delayed fluorescence macrocyclic molecule and preparation method and application thereof 上海大学 2024-05-31 CN claimed
CN-118084943-A Preparation method of novel crystalline coat and application of novel crystalline coat in absolute configuration measurement of natural product 暨南大学 2024-05-28 CN claimed
CN-118005557-A Wide-band gap organic luminescent material and preparation method and application thereof 青岛科技大学 2024-05-10 CN claimed
CN-114354790-B Method for detecting 7 halogenated carbazole compounds in aquatic product 舟山市食品药品检验检测研究院 2024-05-10 CN claimed
CN-117757038-A Copolymer electrolyte material and preparation method and application thereof 华东理工大学 2024-03-26 CN claimed
CN-117486783-A Methoxy-containing carbazole hole transport material and preparation method and application thereof 武汉理工大学 2024-02-02 CN claimed
CN-117165305-A Negative liquid crystal compound and preparation method and application thereof 陕西师范大学 2023-12-05 CN claimed
CN-117092262-A Analysis method for detecting 11 carbazole and halogenated derivatives thereof in shellfish 舟山市食品药品检验检测研究院 2023-11-21 CN claimed
CN-102875447-B Method for preparing 2,7-dibromocarbazole INST CHEMISTRY CO LTD HENAN ACADEMY OF SCIENCES 2014-03-26 CN claimed
CN-103232385-A 2,7-dibromo-N-perfluoro-butylethylcarbazole and preparation method thereof SUZHOU GULI BIOTECHNOLOGY CO 2013-08-07 CN claimed
CN-102489899-B Lead-free soldering paste and preparation method thereof KUNSHAN CHENGLI SOLDER MFG CO LTD 2013-07-31 CN claimed
CN-102924520-A Preparation method of blue phosphorescent host material having bipolar carrier transport performance UNIV SHAANXI SCIENCE & TECH 2013-02-13 CN claimed
CN-102875447-A Method for preparing 2,7-dibromocarbazole INST CHEMISTRY CO LTD HENAN ACADEMY OF SCIENCES 2013-01-16 CN claimed
CN-102827066-A Indenocarbazole derivatives and preparation method thereof UNIV EAST CHINA NORMAL 2012-12-19 CN claimed
CN-102489899-A Lead-free soldering paste and preparation method thereof KUNSHAN CHENGLI SOLDER MFG CO LTD 2012-06-13 CN claimed
US-20050119491-A1 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof SHEFFIELD, THE UNIVERSITY OF (GB) 2005-06-02 US claimed
EP-1453802-A1 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF THE UNIVERSITY OF SHEFFIELD (GB) 2004-09-08 EP claimed
WO-2003050086-A1 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF THE UNIVERSITY OF SHEFFIELD (GB) 2003-06-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050119491-A1 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof CBR3, OR10J3, ORC3 METAP2 4492/4885PDPK1 4630/4885JAK2 1614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.