Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16745425 | 0.93 | TP53 (0.46) | TP53MAPTJAK2HTTKLK7 | |
| SCHEMBL16747994 | 0.90 | TP53 (0.48) | TP53MAPTJAK2HTTKLK7 | |
| SCHEMBL16747993 | 0.90 | JAK2 (0.48) | TP53MAPTJAK2HTTKLK7 | |
| SCHEMBL16745350 | 0.89 | L3MBTL1 (0.43) | TP53MAPTJAK2HTTKLK7 | |
| SCHEMBL16745360 | 0.87 | L3MBTL1 (0.45) | TP53MAPTJAK2HTTKLK7 | |
| SCHEMBL16745376 | 0.87 | L3MBTL1 (0.45) | TP53MAPTJAK2HTTKLK7 | |
| SCHEMBL18193066 | 0.76 | DPP3 (0.45) | MAPTHTTLMNAL3MBTL1MEN1 | |
| SCHEMBL18193063 | 0.73 | ALDH1A1 (0.36) | MAPTCYP1A2CYP3A4KDM4ELMNA | |
| SCHEMBL18193068 | 0.70 | ALDH1A1 (0.38) | MAPTCYP1A2CYP3A4KDM4ELMNA | |
| SCHEMBL16747996 | 0.70 | NPY5R (0.45) | TP53MAPTSMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9481662-B2 | Seriniquinones, melanoma-specific anticancer agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-11-01 | — | — | US | disclosed |