Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17680101 | 1.00 | ALDH1A1 (0.36) | ALDH1A1CYP3A4CHRM1ALOX15ADORA1 | |
| SCHEMBL18193185 | 1.00 | ALDH1A1 (0.36) | ALDH1A1CYP3A4CHRM1ALOX15ADORA1 | |
| SCHEMBL18193241 | 0.95 | ALDH1A1 (0.33) | ALDH1A1CYP3A4CHRM1ALOX15ADORA1 | |
| SCHEMBL18193187 | 0.92 | ALDH1A1 (0.35) | ALDH1A1CYP3A4CHRM1ALOX15ADORA1 | |
| SCHEMBL135547 | 0.92 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CHRM1ALOX15ADORA1 | |
| SCHEMBL18306211 | 0.91 | ALDH1A1 (0.31) | ALDH1A1CYP3A4CHRM1ALOX15ADORA1 | |
| SCHEMBL17677612 | 0.91 | ALDH1A1 (0.35) | ALDH1A1CYP3A4CHRM1ALOX15ADORA1 | |
| SCHEMBL18193189 | 0.91 | ALDH1A1 (0.35) | ALDH1A1CYP3A4CHRM1ALOX15ADORA1 | |
| SCHEMBL18535484 | 0.90 | ALDH1A1 (0.30) | ALDH1A1CYP3A4CHRM1ALOX15ADORA1 | |
| SCHEMBL17680096 | 0.87 | ALDH1A1 (0.37) | ALDH1A1CYP3A4CHRM1ALOX15ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180119046-A1 | LUBRICANT COMPOSITIONS COMPRISING THIOPHOSPHATES AND THIOPHOSPHATE DERIVATIVES | AFTON CHEMICAL CORPORATION | 2018-05-03 | — | — | US | disclosed |
| US-9885003-B2 | Lubricant additive compositions containing thiophosphates and thiophosphate derivatives | AFTON CHEMICAL CORPORATION (US) | 2018-02-06 | — | — | US | disclosed |
| US-9885003-B2 | Lubricant additive compositions containing thiophosphates and thiophosphate derivatives | AFTON CHEMICAL CORPORATION (US) | 2018-02-06 | — | — | US | disclosed |
| US-20170051229-A1 | LUBRICANT ADDITIVE COMPOSITIONS CONTAINING THIOPHOSPHATES AND THIOPHOSPHATE DERIVATIVES | AFTON CHEMICAL CORP (US) | 2017-02-23 | — | — | US | disclosed |
| EP-3133077-A1 | PHOSPHOROUS CONTAINING COMPOUNDS AND USES THEREOF | Afton Chemical Corporation (US) | 2017-02-22 | — | — | EP | disclosed |
| US-9518242-B1 | Lubricant additive compositions containing thiophosphates and thiophosphate derivatives | AFTON CHEMICAL CORPORATION (US) | 2016-12-13 | — | — | US | disclosed |
| US-9518242-B1 | Lubricant additive compositions containing thiophosphates and thiophosphate derivatives | AFTON CHEMICAL CORPORATION (US) | 2016-12-13 | — | — | US | disclosed |
| US-9481696-B1 | Thiophosphates and thiophosphate derivatives as lubricant additives | AFTON CHEMICAL CORPORATION (US) | 2016-11-01 | — | — | US | disclosed |
| US-9481696-B1 | Thiophosphates and thiophosphate derivatives as lubricant additives | AFTON CHEMICAL CORPORATION (US) | 2016-11-01 | — | — | US | disclosed |