SCHEMBL135547

SCHEMBL135547

CCOC(=O)CCSP(=S)(OC(C)C)OC(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.41
HSD17B10 Q99714 2/20 0.41
CYP3A4 P08684 2/20 0.41
ALOX15 P16050 2/20 0.41
CHRM1 P11229 1/20 0.41
ADORA1 P30542 1/20 0.41
TSHR P16473 3/20 0.39
CYP1A2 P05177 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
KDM4E B2RXH2 2/20 0.37
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
MAPT P10636 2/20 0.33
TRPA1 O75762 1/20 0.33
POLB P06746 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17680101 0.92 ALDH1A1 (0.36) ALDH1A1HSD17B10CYP3A4ALOX15CHRM1
SCHEMBL18193232 0.92 ALDH1A1 (0.36) ALDH1A1HSD17B10CYP3A4ALOX15CHRM1
SCHEMBL17680098 0.92 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP3A4ALOX15CHRM1
SCHEMBL18193185 0.92 ALDH1A1 (0.36) ALDH1A1HSD17B10CYP3A4ALOX15CHRM1
SCHEMBL17680080 0.87 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP3A4ALOX15CHRM1
SCHEMBL8565413 0.86 ALDH1A1 (0.39) ALDH1A1HSD17B10CYP3A4ALOX15CHRM1
SCHEMBL16712187 0.85 DGKA (0.40) ALDH1A1MAPT
SCHEMBL18193187 0.84 ALDH1A1 (0.35) ALDH1A1HSD17B10CYP3A4ALOX15CHRM1
SCHEMBL19253713 0.83 TSHR (0.43) ALDH1A1TSHRTDP1GAAL3MBTL1
SCHEMBL17680064 0.83 ENPP2 (0.36) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637632-B2 Hydrolytically stable hydraulic lubricant AFTON CHEMICAL CORPORATION (US) 2026-05-26 US claimed
US-20260117141-A1 HYDROLYTICALLY STABLE HYDRAULIC LUBRICANT AFTON CHEMICAL CORP (US) 2026-04-30 US claimed
EP-4733371-A1 HYDROLYTICALLY STABLE HYDRAULIC LUBRICANT Afton Chemical Corporation (US) 2026-04-29 EP claimed
US-10563148-B2 Lubricant oil composition IDEMITSU KOSAN CO., LTD. (JP) 2020-02-18 US claimed
US-20150184107-A1 LUBRICATING OIL COMPOSITION FOR SHOCK ABSORBER IDEMITSU KOSAN CO., LTD. (JP) 2015-07-02 US claimed
EP-2873717-A1 LUBRICATING OIL COMPOSITION FOR SHOCK ABSORBER Idemitsu Kosan Co., Ltd (JP) 2015-05-20 EP claimed
US-12637632-B2 Hydrolytically stable hydraulic lubricant AFTON CHEMICAL CORPORATION (US) 2026-05-26 US disclosed
US-20260117141-A1 HYDROLYTICALLY STABLE HYDRAULIC LUBRICANT AFTON CHEMICAL CORP (US) 2026-04-30 US disclosed
EP-4733371-A1 HYDROLYTICALLY STABLE HYDRAULIC LUBRICANT Afton Chemical Corporation (US) 2026-04-29 EP disclosed
EP-3464524-B1 LUBRICANT COMPOSITION BASF SE (DE) 2025-04-16 EP disclosed
US-12270004-B2 Lubricant composition BASF SE (DE) 2025-04-08 US disclosed
US-12252567-B2 Acrylate-based copolymer, method for producing said copolymer, friction reducer using said copolymer, and lubricating composition containing said friction reducer ADEKA CORPORATION (JP) 2025-03-18 US disclosed
WO-2025024375-A1 A LUBRICANT COMPOSITION BASF SE (DE) 2025-01-30 WO disclosed
EP-0595771-A1 Phosphorfree lubricant-additives CIBA-GEIGY AG (CH) 1994-05-04 EP disclosed
US-5262072-A Stabilization of a lubricant or hydraulic fluid against oxidation and/or heat degradation CIBA-GEIGY CORPORATION (US) 1993-11-16 US disclosed
EP-0565487-A2 Liquid antioxydants as stabilisers CIBA-GEIGY AG (CH) 1993-10-13 EP disclosed
US-5198130-A Zinc thiophosphates, tetramethylpiperidine derivatives CIBA-GEIGY CORPORATION (US) 1993-03-30 US disclosed
EP-0524145-A1 Multifunctional additives for lubricants CIBA-GEIGY AG (CH) 1993-01-20 EP disclosed
EP-0480875-A1 Lubricating composition CIBA-GEIGY AG (CH) 1992-04-15 EP disclosed
EP-0466639-A1 Lubricant composition CIBA-GEIGY AG (CH) 1992-01-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637632-B2 Hydrolytically stable hydraulic lubricant TST, TASP1, GSTP1 ALDH1A1 1467/4885HSD17B10 1645/4885CYP3A4 2169/4885
US-20260117141-A1 HYDROLYTICALLY STABLE HYDRAULIC LUBRICANT TST, TASP1, GSTP1 ALDH1A1 1467/4885HSD17B10 1645/4885CYP3A4 2169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.