Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL1490297 | 1.00 | TDP1 (0.59) | TDP1FFAR3TSHROR51E2TP53 | |
| Propylene Glycol SCHEMBL28013216 | 1.00 | TDP1 (0.59) | TDP1FFAR3TSHROR51E2TP53 | |
| Propylene Glycol SCHEMBL29127646 | 0.97 | TDP1 (0.56) | TDP1FFAR3TSHROR51E2TP53 | |
| Propylene Glycol SCHEMBL181612 | 0.95 | FFAR3 (0.53) | TDP1FFAR3TSHROR51E2TP53 | |
| Propylene Glycol SCHEMBL351179 | 0.92 | FFAR3 (0.50) | TDP1FFAR3TSHROR51E2TP53 | |
| Butyric Acid SCHEMBL181872 | 0.88 | FFAR3 (0.59) | TDP1FFAR3TSHROR51E2SLC22A6 | |
| Propylene Glycol SCHEMBL445126 | 0.88 | FFAR3 (0.46) | TDP1FFAR3TSHROR51E2TP53 | |
| Propionic Acid SCHEMBL4304135 | 0.85 | FFAR3 (0.62) | TDP1FFAR3TSHRTP53SLC22A6 | |
| Propylene Glycol SCHEMBL28346548 | 0.85 | TDP1 (0.62) | TDP1FFAR3TSHROR51E2TP53 | |
| Isobutanol SCHEMBL11138179 | 0.85 | FFAR3 (0.62) | TDP1FFAR3TSHROR51E2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 341 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986955-A | Water-based bi-component polyurethane finish paint for track traffic interior decoration and preparation method thereof | 青岛爱尔家佳新材料股份有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-112839668-A | Formulations comprising water-soluble particles other than curcumin and curcumin | 斯达必康生命科学私人有限公司 | 2021-05-25 | — | — | CN | claimed |
| CN-110536545-A | A kind of flexible circuit board Halogen silver paste and preparation method thereof | BRETECH ELECTRICAL MAT CO LTD | 2019-12-03 | — | — | CN | claimed |
| CN-104241593-B | Charge storage element and battery module | 株式会社杰士汤浅国际 | 2019-01-08 | — | — | CN | claimed |
| EP-2816635-B1 | Electric storage device and electric storage module | GS YUASA INT LTD (JP) | 2016-09-21 | — | — | EP | claimed |
| US-20140376160-A1 | ELECTRIC STORAGE DEVICE AND ELECTRIC STORAGE MODULE | GS YUASA INTERNATIONAL LTD. (JP) | 2014-12-25 | — | — | US | claimed |
| EP-2816635-A1 | Electric storage device and electric storage module | GS Yuasa International Ltd. (JP) | 2014-12-24 | — | — | EP | claimed |
| CN-104241593-A | ELECTRIC STORAGE DEVICE AND ELECTRIC STORAGE MODULE | GS YUASA INT LTD | 2014-12-24 | — | — | CN | claimed |
| EP-0851298-B1 | Use of a solvent mixture for roller coating a radiation sensitive composition | CLARIANT FINANCE BVI LTD (VG) | 2004-06-16 | — | — | EP | claimed |
| US-20030036489-A1 | Consumable composition comprising perfumed particles and article containing the same | THE PROCTER & GAMBLE COMPANY | 2003-02-20 | — | — | US | claimed |
| WO-2002090479-A1 | PERFUMED PARTICLES AND ARTICLES CONTAINING THE SAME | THE PROCTER & GAMBLE COMPANY (US) | 2002-11-14 | — | — | WO | claimed |
| WO-2002090481-A1 | COMPOSITIONS AND ARTICLES FOR EFFECTIVE DEPOSITION OF PERFUME | THE PROCTER & GAMBLE COMPANY (US) | 2002-11-14 | — | — | WO | claimed |
| US-6415614-B1 | CONTROLLING VAPOR PRESSURE OF MIXTURE | VISTEON GLOBAL TECHNOLOGIES, INC. | 2002-07-09 | — | — | US | claimed |
| US-5403426-A | Surface treatment | HERCULES INCORPORATED (US) | 1995-04-04 | — | — | US | claimed |
| EP-0349301-A2 | Positive-type photoresist composition | MITSUBISHI KASEI CORPORATION (JP) | 1990-01-03 | — | — | EP | claimed |
| US-4159925-A | Process for isolating propylene glycol diesters in the preparation of propylene oxide | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-03 | — | — | US | claimed |
| US-3982026-A | PROPYLENE GLYCOL ESTERS OF PROPIONIC ACID | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-09-21 | — | — | US | claimed |
| US-3952071-A | ALUMINUM HALIDE-POLYHYDRIC ALCOHOL DERIVATIVE CATALYST | LION FAT & OIL CO., LTD. (JA) | 1976-04-20 | — | — | US | claimed |
| US-20240410055-A1 | METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS | MERCK PATENT GMBH (DE) | 2024-12-12 | — | — | US | disclosed |
| US-3952071-A | ALUMINUM HALIDE-POLYHYDRIC ALCOHOL DERIVATIVE CATALYST | LION FAT & OIL CO., LTD. (JA) | 1976-04-20 | — | — | US | disclosed |