Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL28013216 | 0.95 | TDP1 (0.59) | FFAR3TDP1TSHRALDH1A1OR51E2 | |
| Propylene Glycol SCHEMBL181936 | 0.95 | TDP1 (0.59) | FFAR3TDP1TSHRALDH1A1OR51E2 | |
| Propylene Glycol SCHEMBL1490297 | 0.95 | TDP1 (0.59) | FFAR3TDP1TSHRALDH1A1OR51E2 | |
| Propylene Glycol SCHEMBL29127646 | 0.92 | TDP1 (0.56) | FFAR3TDP1TSHRALDH1A1OR51E2 | |
| Propylene Glycol SCHEMBL11062962 | 0.89 | TDP1 (0.59) | FFAR3TDP1TSHRALDH1A1OR51E2 | |
| Propylene Glycol SCHEMBL36041 | 0.89 | — | — | |
| Propylene Glycol SCHEMBL358822 | 0.89 | TDP1 (0.67) | FFAR3TDP1TSHRALDH1A1OR51E2 | |
| Propylene Glycol SCHEMBL21828462 | 0.89 | TDP1 (0.67) | FFAR3TDP1TSHRALDH1A1OR51E2 | |
| Propylene Glycol SCHEMBL8850998 | 0.89 | TDP1 (0.67) | FFAR3TDP1TSHRALDH1A1OR51E2 | |
| Propylene Glycol SCHEMBL49092 | 0.89 | TDP1 (0.67) | FFAR3TDP1TSHRALDH1A1OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6415614-B1 | CONTROLLING VAPOR PRESSURE OF MIXTURE | VISTEON GLOBAL TECHNOLOGIES, INC. | 2002-07-09 | — | — | US | claimed |
| US-12637578-B2 | Ink jet ink composition and recording method | SEIKO EPSON CORPORATION (JP) | 2026-05-26 | — | — | US | disclosed |
| US-12637804-B2 | Ink jet recording method | SEIKO EPSON CORPORATION (JP) | 2026-05-26 | — | — | US | disclosed |
| US-12629934-B2 | Recording method and recording device | SEIKO EPSON CORPORATION (JP) | 2026-05-19 | — | — | US | disclosed |
| US-12630728-B2 | Ink set and recording method | SEIKO EPSON CORPORATION (JP) | 2026-05-19 | — | — | US | disclosed |
| US-12630973-B2 | Recording method | SEIKO EPSON CORPORATION (JP) | 2026-05-19 | — | — | US | disclosed |
| US-12624242-B2 | Water-based coloring composition, coloring method, pigment dispersion liquid, and metal pigment producing method | SEIKO EPSON CORPORATION (JP) | 2026-05-12 | — | — | US | disclosed |
| US-20260125850-A1 | Pretreatment Liquid For Textile Printing And Textile Printing Method | SEIKO EPSON CORP (JP) | 2026-05-07 | — | — | US | disclosed |
| US-20260116073-A1 | Maintenance Method And Recording Apparatus | SEIKO EPSON CORP (JP) | 2026-04-30 | — | — | US | disclosed |
| US-12584030-B2 | Ink jet ink composition and recording method | SEIKO EPSON CORPORATION (JP) | 2026-03-24 | — | — | US | disclosed |
| US-7604695-B2 | Ink composition | TOYO INK MFG. CO., LTD. (JP) | 2009-10-20 | — | — | US | disclosed |
| EP-2083054-A1 | NONAQUEOUS INKJET INK AND INK SET | Toyo Ink Mfg. Co. Ltd. (JP) | 2009-07-29 | — | — | EP | disclosed |
| US-7407536-B2 | Ink composition | TOYO INK MFG. CO., LTD. (JP) | 2008-08-05 | — | — | US | disclosed |
| EP-1790700-B1 | Organic solvent based ink Composition | TOYO INK MFG CO (JP) | 2008-07-02 | — | — | EP | disclosed |
| US-20070119342-A1 | Ink composition | TOYO INK MFG. CO., LTD. (JP) | 2007-05-31 | — | — | US | disclosed |
| US-20070119335-A1 | For printing on non-absorbable printing media, containing as a solvent a a hydrofuran-3-one, hydropyranone, oxazolinone, morpholin-3-one or 1,3-hydrooxazin-4-one; odorless, excellent safety and health properties, resin solubility, printing stability and drying properties and causes no corrosion | TOYO INK MFG. CO., LTD. (JP) | 2007-05-31 | — | — | US | disclosed |
| EP-1790699-A1 | Ink composition | TOYO INK MFG. CO., LTD. (JP) | 2007-05-30 | — | — | EP | disclosed |
| EP-1790700-A1 | Organic solvent based ink Composition | TOYO INK MFG. CO., LTD. (JP) | 2007-05-30 | — | — | EP | disclosed |
| US-3933518-A | CHLORINATED ALIPHATIC HYDROCARBONS, ALKYLENE GLYCOL ALKANOATE | THE DOW CHEMICAL COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933517-A | Compositions for reflowing organic surfaces | THE DOW CHEMICAL COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125850-A1 | Pretreatment Liquid For Textile Printing And Textile Printing Method | ADH1A, RARA, RBP4 | FFAR3 1610/4885TDP1 1719/4885TSHR 4678/4885 |
| US-12624242-B2 | Water-based coloring composition, coloring method, pigment dispersion liquid, and metal pigment producing method | HAO2, PHOSPHO1, HAO1 | FFAR3 757/4885TDP1 2302/4885TSHR 1160/4885 |
| US-12637578-B2 | Ink jet ink composition and recording method | TYR, RB1, WNT1 | FFAR3 3850/4885TDP1 2124/4885TSHR 3228/4885 |
| US-12630973-B2 | Recording method | DOT1L, EMD, EZH2 | FFAR3 4216/4885TDP1 293/4885TSHR 3373/4885 |
| US-20260116073-A1 | Maintenance Method And Recording Apparatus | WFS1, HCN2, SMN1; SMN2 | FFAR3 4447/4885TDP1 1506/4885TSHR 2142/4885 |
| US-12629934-B2 | Recording method and recording device | HCN2, MC1R, TYR | FFAR3 3593/4885TDP1 518/4885TSHR 2648/4885 |
| US-12630728-B2 | Ink set and recording method | DOT1L, SET, ALKBH3 | FFAR3 4053/4885TDP1 747/4885TSHR 4820/4885 |
| US-12637804-B2 | Ink jet recording method | IK, PRPH, SLC6A19 | FFAR3 3092/4885TDP1 521/4885TSHR 1740/4885 |
| US-12584030-B2 | Ink jet ink composition and recording method | LSM8, SMURF1, SMAD3 | FFAR3 3775/4885TDP1 780/4885TSHR 3709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.