Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL181936 | 0.92 | TDP1 (0.59) | FFAR3TDP1TSHROR51E2TP53 | |
| Propylene Glycol SCHEMBL28013216 | 0.92 | TDP1 (0.59) | FFAR3TDP1TSHROR51E2TP53 | |
| Propylene Glycol SCHEMBL1490297 | 0.92 | TDP1 (0.59) | FFAR3TDP1TSHROR51E2TP53 | |
| Propylene Glycol SCHEMBL29127646 | 0.90 | TDP1 (0.56) | FFAR3TDP1TSHROR51E2TP53 | |
| Propylene Glycol SCHEMBL181612 | 0.87 | FFAR3 (0.53) | FFAR3TDP1TSHROR51E2TP53 | |
| Propylene Glycol SCHEMBL28578077 | 0.87 | TDP1 (0.53) | FFAR3TDP1TSHROR51E2TP53 | |
| Propylene Glycol SCHEMBL28400237 | 0.87 | TDP1 (0.59) | TDP1TSHROR51E2TP53TGFBR1 | |
| Propylene Glycol SCHEMBL445126 | 0.86 | FFAR3 (0.46) | FFAR3TDP1TSHROR51E2TP53 | |
| Propylene Glycol SCHEMBL28218462 | 0.86 | TDP1 (0.46) | FFAR3TDP1TSHROR51E2TP53 | |
| Propylene Glycol SCHEMBL2481279 | 0.85 | TDP1 (0.50) | FFAR3TDP1TSHROR51E2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 860 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120137518-B | Yellowing-resistant paint for cement-based floor finish and application method thereof | 万华化学集团股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| US-20260055234-A1 | POLYCARBONATE OLIGOMER HAVING UNSATURATED DOUBLE BONDS, PREPARATION METHOD THEREFOR, AND CURABLE COMPOSITION | SWANCOR INNOVATION & INCUBATION CO LTD (TW) | 2026-02-26 | — | — | US | claimed |
| EP-4682196-A1 | POLYCARBONATE OLIGOMER HAVING UNSATURATED DOUBLE BONDS, PREPARATION METHOD THEREFOR, CURABLE COMPOSITION, AND PREPARATION METHOD FOR LOW-DIELECTRIC CURED PRODUCT | Swancor Innovation & Incubation Co., Ltd. (TW) | 2026-01-21 | — | — | EP | claimed |
| WO-2025123924-A1 | HIGH-WEAR-RESISTANCE ELECTRICALLY CONDUCTIVE CARBON PASTE FOR PCB, AND PREPARATION METHOD THEREFOR | 上海宝银电子材料有限公司 | 2025-06-19 | — | — | WO | claimed |
| CN-120137518-A | Yellowing-resistant paint for cement-based floor finish and application method thereof | 万华化学集团股份有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-119978300-A | Water-based curing agent, preparation method thereof and water-based paint | 濮阳展辰新材料有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119927497-A | High-temperature-resistant and oxidation-resistant solder paste and preparation method thereof | 深圳市新义金属科技有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-114556216-B | Positive photosensitive resin composition and display element using same | 株式会社东进世美肯 | 2025-04-25 | — | — | CN | claimed |
| CN-119889761-A | High-performance conductive silver paste for metal copper foil and preparation method thereof | 上海宝银电子材料有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119805887-A | Polyimide film stripping liquid and preparation method and application thereof | 深圳市化讯半导体材料有限公司 | 2025-04-11 | — | — | CN | claimed |
| US-20100195232-A1 | Ink Composition for Color Filter, Method for Preparing a Color Filter Using the Same, and Color Filter | CHEIL INDUSTRIES INC. (KR) | 2010-08-05 | — | — | US | claimed |
| US-20090176936-A1 | Ink composition and method of forming a pattern using the same | LG DISPLAY CO., LTD. (KR) | 2009-07-09 | — | — | US | claimed |
| WO-2009051293-A1 | INK COMPOSITION FOR COLOR FILTER, METHOD FOR PREPARING A COLOR FILTER USING THE SAME, AND COLOR FILTER | CHEIL INDUSTRIES INC. (KR) | 2009-04-23 | — | — | WO | claimed |
| US-7393419-B2 | Conductive adhesive rework method | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2008-07-01 | — | — | US | claimed |
| US-20080017223-A1 | CONDUCTIVE ADHESIVE REWORK METHOD | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2008-01-24 | — | — | US | claimed |
| US-20050256241-A1 | Metal filler particles dispersed in solvent-free hybrid epoxy polymer matrix; electronics; semiconductors; heat sinks | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2005-11-17 | — | — | US | claimed |
| CN-1634851-A | Clean production method for propylene glycol monomethyl ether acetate | JIANGYIN YIDA CHEMICAL CO LTD (CN) | 2005-07-06 | — | — | CN | claimed |
| US-6652665-B1 | Immersing and aggitating in preheated solution containing quaternary ammonium fluoride and hydrophobic nonhydroxylic aprotic solvent | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2003-11-25 | — | — | US | claimed |
| US-6491729-B1 | Dry-cleaning solvent composition | Lee, Chin Yen (TW) | 2002-12-10 | — | — | US | claimed |
| US-6379860-B1 | RESIN OBTAINED BY REACTION OF ALKALI-SOLUBLE RESIN HAVING PHENOLIC HYDROXYL GROUPS WITH ENOL ETHER DECOMPOSES IN ACID TO INCREASE SOLUBILITY; HEAT RESISTANCE, SENSITIVIY, RESOLUTION; GENERATES ACID UPON ACTINIC RADIATION EXPOSURE | FUJI PHOTO FILM CO., LTD. (JP) | 2002-04-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260055234-A1 | POLYCARBONATE OLIGOMER HAVING UNSATURATED DOUBLE BONDS, PREPARATION METHOD THEREFOR, AND CURABLE COMPOSITION | ADH1A, PCNA, ADH1C | FFAR3 157/4885TDP1 2365/4885TSHR 4333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.