Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25698895 | 0.82 | BIRC2 (0.34) | BIRC2 | |
| SCHEMBL23139621 | 0.82 | BIRC2 (0.34) | BIRC2 | |
| Hydrochloric Acid SCHEMBL25337896 | 0.80 | HPGD (0.34) | BIRC2 | |
| Hydrochloric Acid SCHEMBL25337894 | 0.80 | HPGD (0.34) | BIRC2 | |
| SCHEMBL26089260 | 0.79 | BIRC2 (0.41) | BIRC2HRH4 | |
| SCHEMBL26089257 | 0.79 | BIRC2 (0.41) | BIRC2HRH4 | |
| SCHEMBL12350484 | 0.78 | HTR6 (0.36) | BIRC2 | |
| SCHEMBL14856418 | 0.78 | HTR6 (0.36) | BIRC2 | |
| SCHEMBL17631062 | 0.77 | BIRC2 (0.32) | BIRC2 | |
| Hydrochloric Acid SCHEMBL2237196 | 0.77 | HTR6 (0.35) | BIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3088401-A1 | (6S,9aS)-N-BENZYL-6-[(4-HYDROXYPHENYL)METHYL]-4,7-DIOXO-8-({6-[3-(PIPERAZINE-1-YL)AZETIDINE-1-YL]PYRIDINE-2-YL}METHYL)-2-(PROP-2-EN-1-YL)-OCTAHYDRO-1H-PYRAZINO[2,1-c][1,2,4]TRIAZINE-1-CARBOXAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2016-11-02 | — | — | EP | disclosed |