SCHEMBL181965

SCHEMBL181965

C=Cc1c(Cl)cccc1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
KMT2A Q03164 2/20 0.55
MEN1 O00255 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
CYP1A2 P05177 2/20 0.43
CYP2A6 P11509 2/20 0.43
TSHR P16473 3/20 0.42
LMNA P02545 1/20 0.42
HSP90AA1 P07900 1/20 0.41
SLC22A1 O15245 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA2A P08913 1/20 0.40
CHRM1 P11229 1/20 0.40
ADRA2B P18089 1/20 0.40
ADRA2C P18825 1/20 0.40
MAOA P21397 1/20 0.40
DRD1 P21728 1/20 0.40
TBXA2R P21731 1/20 0.40
SLC6A2 P23975 1/20 0.40
ADRA1D P25100 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27920138 0.97 ALDH1A1 (0.52) ALDH1A1KMT2AMEN1TDP1CYP1A2
SCHEMBL23361556 0.85 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1TDP1CYP1A2
SCHEMBL1207128 0.85 ALDH1A1 (0.62) ALDH1A1KMT2AMEN1TDP1CYP1A2
SCHEMBL29281933 0.84 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1TDP1CYP2A6
SCHEMBL31256460 0.83 ALDH1A1 (0.44) ALDH1A1KMT2AMEN1TDP1CYP1A2
SCHEMBL29700809 0.83 HPGD (0.47) ALDH1A1KMT2AMEN1TDP1CYP1A2
SCHEMBL26026901 0.83 TSHR (0.48) ALDH1A1KMT2AMEN1TDP1CYP1A2
SCHEMBL1988801 0.83 TSHR (0.50) ALDH1A1KMT2AMEN1TDP1CYP1A2
SCHEMBL23043311 0.83 ALDH1A1 (0.44) ALDH1A1KMT2AMEN1TDP1CYP1A2
SCHEMBL8363460 0.83 ALDH1A1 (0.44) ALDH1A1KMT2AMEN1TDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3044 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570887-B2 Ultra-high molecular weight (UHMW) branched block copolymer viscosifier for water based drilling fluids SAUDI ARABIAN OIL COMPANY (SA) 2026-03-10 US claimed
EP-3902854-B1 POLYMERIC COMPOSITION COMPRISING A THERMOPLASTIC ELASTOMER WITH BUTADIENE AND STYRENE BLOCKS AND A COMPATIBLE PLASTICISER MICHELIN & CIE (FR) 2025-10-15 EP claimed
US-12428501-B2 Method for producing removable pressure-sensitive adhesives (PSAs) using bio-based starting materials THE UNIVERSITY OF THE BASQUE COUNTRY (ES) 2025-09-30 US claimed
US-12428552-B2 Polymeric composition comprising a thermoplastic elastomer with butadiene and styrene blocks and a compatible plasticizer COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2025-09-30 US claimed
US-12391864-B2 Development of ultra-high molecular weight (UHMW) branched block copolymer shale inhibitor for water based drilling fluid SAUDI ARABIAN OIL COMPANY (SA) 2025-08-19 US claimed
US-12378465-B2 Development of ultra-high molecular weight (UHMW) branched block copolymer drag reducer with improved mechanical and chemical stability SAUDI ARABIAN OIL COMPANY (SA) 2025-08-05 US claimed
EP-3647333-B1 CURABLE PETROLEUM RESIN, PREPARATION METHOD THEREFOR, AND USE THEREOF KOLON INC (KR) 2025-06-18 EP claimed
US-12312434-B2 Tire comprising a polymeric composition comprising a thermoplastic elastomer comprising units derived from diphenylene ether monomer COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2025-05-27 US claimed
EP-3894235-B1 TYRE COMPRISING A POLYMERIC COMPOSITION COMPRISING A THERMOPLASTIC ELASTOMER COMPRISING UNITS DERIVED FROM DIPHENYLENE ETHER MONOMER MICHELIN & CIE (FR) 2024-10-23 EP claimed
CN-118724934-A Mechanochemical synthesis of alpha-haloalkylboron esters 西安交通大学 2024-10-01 CN claimed
US-4956123-A REACTING A STYRENE TYPE COMPOUND WITH A DIHALOACYL PEROXIDE TO MAKE A FLUOROALKYLAROMATIC ESTER NIPPON OILS & FATS COMPANY, LTD. (JP) 1990-09-11 US claimed
US-4698393-A FRIEDEL CRAFTS CATALYSTS AND SUSPENSION POLYMERIZATION; MATERIALS HANDLING RAYCHEM CORPORATION (US) 1987-10-06 US claimed
EP-0092794-B1 LIGHT-SENSITIVE PRINTING PLATE FUJI PHOTO FILM CO., LTD. (JP) 1987-07-15 EP claimed
US-4587203-A USING A DEVELOPMENT SOLVENT AND RINSING NONSOLVENT; SILANE COUPLING INTERLAYER; DIMENSIONAL STABILITY AND SHARPNESS OF IMAGE HUGHES AIRCRAFT COMPANY (US) 1986-05-06 US claimed
EP-0174207-A2 Preparation of poly(arylene ether ketones) RAYCHEM CORPORATION (a Delaware corporation) (US) 1986-03-12 EP claimed
US-4557994-A MICROPATTERN OF TERPOLYMER RESISTANT TO RUBBING AND PRESSURE FUJI PHOTO FILM CO., LTD. (JP) 1985-12-10 US claimed
US-4535054-A IRRADIATION TO GIVE NEGATIVE PATTERN IMAGE, DEVELOPMENT BY DISSOLUING UNEXPOSED POLYMER WITH SOLVENT AND RINSING HUGHES AIRCRAFT COMPANY (US) 1985-08-13 US claimed
EP-0092794-A2 Light-sensitive printing plate FUJI PHOTO FILM CO., LTD. (JP) 1983-11-02 EP claimed
US-4306780-A Highly refractive copolymer of an ethylinically unsaturated alkylene oxide of bis-phenol-A and an ethylinically unsaturated aromatic compound for lens and a lens prepared therefrom HOYA LENS CORPORATION (JP) 1981-12-22 US claimed
US-4168365-A Flame-retardant phenolic resin MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1979-09-18 US claimed