SCHEMBL29700809

SCHEMBL29700809

C=Cc1c(F)cccc1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.47
RAB9A P51151 4/20 0.47
TDP1 Q9NUW8 2/20 0.46
KCNH2 Q12809 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
MAT2A P31153 1/20 0.46
SMN1; SMN2 Q16637 5/20 0.45
LMNA P02545 3/20 0.45
ALOX12 P18054 1/20 0.45
ATM Q13315 1/20 0.45
ALDH1A1 P00352 5/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 1/20 0.44
HTT P42858 3/20 0.44
MAPT P10636 3/20 0.44
MDM4 O15151 1/20 0.44
MDM2 Q00987 1/20 0.44
NPC1 O15118 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3339035 1.00 HPGD (0.47) HPGDRAB9ATDP1KCNH2CYP1A2
SCHEMBL181965 0.83 ALDH1A1 (0.55) HPGDRAB9ATDP1CYP1A2SMN1; SMN2
SCHEMBL193995 0.83 NFE2L2 (0.46) HPGDRAB9ATDP1KCNH2MAT2A
SCHEMBL21055946 0.81 ALDH1A1 (0.48) HPGDRAB9ATDP1KCNH2CYP1A2
SCHEMBL27920138 0.80 ALDH1A1 (0.52) HPGDRAB9ATDP1CYP1A2SMN1; SMN2
SCHEMBL8186920 0.77 TDP1 (0.46) HPGDRAB9ATDP1KCNH2CYP1A2
SCHEMBL8186922 0.77 ALDH1A1 (0.46) HPGDRAB9ATDP1KCNH2CYP1A2
SCHEMBL5412758 0.77 KCNH2 (0.50) HPGDRAB9ATDP1KCNH2CYP1A2
SCHEMBL154430 0.77 ALDH1A1 (0.70) HPGDRAB9ATDP1KCNH2CYP1A2
SCHEMBL23361556 0.74 ALDH1A1 (0.46) HPGDRAB9ATDP1CYP1A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4251696-A1 UV RESISTANT SMMA COPOLYMERS WITH LOW HAZE AND HIGH CLARITY INEOS Styrolution Group GmbH (DE) 2023-10-04 EP disclosed
WO-2022112590-A1 UV RESISTANT SMMA COPOLYMERS WITH LOW HAZE AND HIGH CLARITY INEOS STYROLUTION GROUP GMBH (DE) 2022-06-02 WO disclosed