SCHEMBL1819745

SCHEMBL1819745

CCCCCC([SiH2]C(C)(OC(C)C)OC(C)C)[SiH2]C(C)(OC(C)C)OC(C)C

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.35
SPHK1 Q9NYA1 1/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1821356 0.80 OPRM1 (0.33) OPRM1CA1
SCHEMBL1821876 0.77 OPRM1 (0.31) OPRM1
SCHEMBL11232060 0.68 OPRM1 (0.46) OPRM1SPHK1CA1
SCHEMBL6708524 0.67 OPRM1 (0.41) OPRM1SPHK1CA1
SCHEMBL1822361 0.67
SCHEMBL6706863 0.65 OPRM1 (0.39) OPRM1SPHK1
SCHEMBL6708355 0.65 OPRM1 (0.39) OPRM1SPHK1
SCHEMBL6707422 0.65 OPRM1 (0.39) OPRM1SPHK1
SCHEMBL1123109 0.65 OPRM1 (0.34) OPRM1
SCHEMBL6709895 0.65 OPRM1 (0.39) OPRM1SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9181356-B2 Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORPORATION (TW) 2015-11-10 US disclosed
EP-2316862-B1 Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP (TW) 2013-12-25 EP disclosed
CN-101829600-B Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP 2012-08-29 CN disclosed
US-20110105694-A1 HYDROGENATION CATALYST COMPOSITION AND HYDROGENATION METHOD THEREOF TSRC CORPORATION (TW) 2011-05-05 US disclosed
EP-2316862-A1 Hydrogenation catalyst composition and hydrogenation method thereof TSRC Corporation (TW) 2011-05-04 EP disclosed
CN-101829600-A Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP 2010-09-15 CN disclosed