Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | ITGAL | P20701 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29498093 | 0.81 | MAPT (0.69) | L3MBTL1MAPTCCR1CCR8HPRT1 | |
| SCHEMBL8140334 | 0.81 | MAPT (0.69) | L3MBTL1MAPTCCR1CCR8HPRT1 | |
| SCHEMBL13906866 | 0.79 | NR4A2 (0.56) | L3MBTL1MAPTCCR1CCR8CYP2A6 | |
| SCHEMBL22686771 | 0.76 | L3MBTL1 (0.61) | L3MBTL1MAPTCCR1CCR8CYP2A6 | |
| SCHEMBL21658782 | 0.75 | NR4A2 (0.40) | L3MBTL1MAPTCCR1CCR8ALDH1A1 | |
| SCHEMBL18197787 | 0.75 | NR4A2 (0.47) | L3MBTL1MAPTCCR1CCR8ALDH1A1 | |
| SCHEMBL27299384 | 0.75 | PLAU (0.50) | L3MBTL1MAPTCCR1CCR8ALDH1A1 | |
| SCHEMBL27571287 | 0.75 | NCF1 (0.53) | HPRT1CYP2A6ALDH1A1CYP1B1CYP3A4 | |
| SCHEMBL21556238 | 0.75 | MAPT (0.64) | L3MBTL1MAPTCCR1CCR8HPRT1 | |
| SCHEMBL1845197 | 0.73 | BACE1 (0.60) | MAPTALDH1A1RAB9AMAOALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3088397-A1 | COMPOUNDS THAT ABROGATE THE CELL CYCLE G2 CHECKPOINT FOR USE IN THE TREATMENT OF CANCER | Canbas Co. Ltd. (JP) | 2016-11-02 | — | — | EP | disclosed |