Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 4/20 | 0.34 |
| ▸ | FEN1 | P39748 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20064783 | 0.88 | ADORA3 (0.40) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL18198506 | 0.87 | KDM4E (0.36) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL18198051 | 0.80 | HPGD (0.46) | KDM4EALDH1A1HPGDPOLBNPSR1 | |
| SCHEMBL18198380 | 0.80 | HPGD (0.46) | KDM4EALDH1A1HPGDPOLBNPSR1 | |
| SCHEMBL23953980 | 0.80 | HPGD (0.46) | KDM4EALDH1A1HPGDPOLBNPSR1 | |
| SCHEMBL18198326 | 0.79 | KDM4E (0.36) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL18198351 | 0.78 | MCL1 (0.36) | KDM4EALDH1A1MAPTTP53 | |
| SCHEMBL20064800 | 0.77 | KDM4E (0.35) | KDM4EALDH1A1MAPTTP53 | |
| SCHEMBL20074019 | 0.77 | MET (0.35) | ALOX5APFEN1KDM4EMAPTPOLB | |
| SCHEMBL20064762 | 0.76 | ADORA2A (0.42) | KDM4EALDH1A1HPGDMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016174079-A1 | RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-11-03 | — | — | WO | disclosed |