SCHEMBL18199028

SCHEMBL18199028

CCC(C)(C)C(=O)OC(C)(C(F)(F)F)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 3/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
MAPK1 P28482 1/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
GLA P06280 1/20 0.30
CYP17A1 P05093 1/20 0.30
CYP19A1 P11511 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL47390 0.81 KMT2A (0.35) EPHX2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL119887 0.80 KMT2A (0.34) EPHX2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL10148640 0.80 KMT2A (0.34) EPHX2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL2740754 0.80 KMT2A (0.34) EPHX2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL19978612 0.78 KMT2A (0.33) EPHX2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL18802878 0.77 MEN1 (0.33) EPHX2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL106979 0.77 MEN1 (0.32) EPHX2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL19753662 0.77 MEN1 (0.33) EPHX2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL22402975 0.76 ALDH1A1 (0.35) EPHX2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL25468020 0.75 GLA (0.33) MEN1KMT2AMAPK1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230194986-A1 CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-22 US disclosed
US-20160320699-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-11-03 US disclosed