Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.62 |
| ▸ | CA1 | P00915 | 7/20 | 0.62 |
| ▸ | CA2 | P00918 | 7/20 | 0.62 |
| ▸ | CA9 | Q16790 | 7/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16520524 | 0.91 | CA12 (0.60) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL18199289 | 0.89 | CA12 (0.61) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL18202511 | 0.84 | CA12 (0.55) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL12461819 | 0.83 | CA12 (0.67) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL30283341 | 0.83 | CA12 (0.61) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL29269474 | 0.83 | CA12 (0.61) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL1005270 | 0.82 | CA12 (0.65) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL19000426 | 0.82 | CA12 (0.56) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL29890066 | 0.82 | CA12 (0.56) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL23901546 | 0.81 | CA12 (0.61) | CA12CA1CA2CA9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318861-A1 | NOVEL PRODRUGS OF DITHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318861-A1 | NOVEL PRODRUGS OF DITHIOL MUCOLYTIC AGENTS | MUC1, MGMT, ESD | CA12 319/4885CA1 624/4885CA2 2098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.