SCHEMBL18200090

SCHEMBL18200090

Cc1ccc(S(=O)(=O)Cl)c(C)n1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 2/20 0.36
CCR1 P32246 1/20 0.36
RAB9A P51151 1/20 0.36
CCR5 P51681 1/20 0.36
HSD11B1 P28845 1/20 0.36
ALDH1A1 P00352 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
KMT2A Q03164 2/20 0.33
GAA P10253 1/20 0.33
GLO1 Q04760 1/20 0.33
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
S100A4 P26447 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
CYP1A2 P05177 1/20 0.31
EGFR P00533 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28696903 0.81 KMT2A (0.42) TRPV4CCR1RAB9ACCR5HSD11B1
SCHEMBL30540039 0.81 TRPV4 (0.39) TRPV4ALDH1A1HSD17B10TDP1GAA
SCHEMBL540698 0.81 TRPV4 (0.39) TRPV4ALDH1A1HSD17B10TDP1GAA
SCHEMBL26442411 0.80 L3MBTL1 (0.41) CCR1RAB9ACCR5HSD11B1ALDH1A1
SCHEMBL31717288 0.79 TRPV4 (0.34) TRPV4CCR1RAB9ACCR5HSD11B1
SCHEMBL31645084 0.79 KMT2A (0.36) TRPV4CCR1RAB9ACCR5HSD11B1
SCHEMBL25373682 0.79 TRPV4 (0.34) TRPV4ALDH1A1HSD17B10TDP1KMT2A
SCHEMBL21777236 0.79 TRPV4 (0.34) TRPV4ALDH1A1HSD17B10TDP1KMT2A
SCHEMBL18200089 0.78 CA1 (0.39) CCR1RAB9ACCR5ALDH1A1GAA
SCHEMBL8432927 0.78 MYC (0.36) CCR1RAB9ACCR5HSD11B1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250161281-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. 2025-05-22 US disclosed
WO-2016173493-A1 SULFONYLAMINOCARBONYL DERIVATIVE, PHARMACEUTICAL COMPOSITION AND USES THEREOF SHANGHAI DE NOVO PHARMATECH CO. LTD. (CN) 2016-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250161281-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF EBPL, EBP, CREBBP TRPV4 4584/4885CCR1 1453/4885RAB9A 3930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.