Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 18/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16682635 | 0.88 | GRM5 (0.48) | GRM5GRM1POLB | |
| SCHEMBL18200199 | 0.85 | GRM5 (0.52) | GRM5POLB | |
| SCHEMBL16682723 | 0.84 | GRM5 (0.67) | GRM5POLB | |
| SCHEMBL16711314 | 0.81 | GRM5 (0.50) | GRM5GRM1 | |
| SCHEMBL16711195 | 0.80 | GRM5 (0.50) | GRM5GRM1 | |
| SCHEMBL24277112 | 0.80 | GRM5 (0.44) | GRM5 | |
| SCHEMBL26645345 | 0.79 | CYP3A4 (0.48) | GRM5POLBCYP3A4CYP3A5 | |
| SCHEMBL26645758 | 0.78 | GRM5 (0.43) | GRM5POLBCYP3A4CYP3A5 | |
| SCHEMBL16682712 | 0.78 | GRM5 (0.58) | GRM5POLB | |
| SCHEMBL30622995 | 0.78 | CFTR (0.44) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318933-A1 | FUSED PYRAZOLE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318933-A1 | FUSED PYRAZOLE DERIVATIVE | DRD4, DRD2, DRD3 | GRM5 185/4885GRM1 198/4885POLB 3812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.