SCHEMBL18200342

SCHEMBL18200342

O=P(c1ccccc1)(c1ccccc1)c1cccc(-c2cccc(-c3nc4ccccc4c4c3ccc3ccccc34)c2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.37
ALDH1A1 P00352 3/20 0.37
HPGD P15428 2/20 0.37
LMNA P02545 2/20 0.37
HTT P42858 2/20 0.37
NPC1 O15118 1/20 0.37
NPY1R P25929 1/20 0.37
NPY2R P49146 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ADORA2A P29274 3/20 0.35
CYP1A1 P04798 2/20 0.33
KDM4E B2RXH2 2/20 0.33
DHODH Q02127 2/20 0.33
ACP3 P15309 1/20 0.33
CYP1A2 P05177 1/20 0.33
FYN P06241 1/20 0.33
MAPK3 P27361 1/20 0.33
AHR P35869 1/20 0.33
PAX8 Q06710 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17034902 0.97 MAPT (0.39) MAPTALDH1A1HPGDLMNAHTT
SCHEMBL18200830 0.95 DHODH (0.39) MAPTALDH1A1HPGDLMNAHTT
SCHEMBL18200831 0.95 MAPT (0.37) MAPTALDH1A1HPGDLMNAHTT
SCHEMBL22606533 0.93 MAPT (0.38) MAPTALDH1A1HPGDLMNAHTT
SCHEMBL17035055 0.92 DHFR (0.37) MAPTALDH1A1HPGDLMNAHTT
SCHEMBL17034946 0.90 MEN1 (0.35) MAPTALDH1A1HPGDLMNAHTT
SCHEMBL22606532 0.89 MAPT (0.39) MAPTALDH1A1HPGDLMNAHTT
SCHEMBL18200531 0.89 MAPT (0.33) MAPTALDH1A1HPGDLMNAHTT
SCHEMBL18200636 0.88 MAPT (0.44) MAPTALDH1A1HPGDLMNAHTT
SCHEMBL20249898 0.88 CSNK2A2 (0.35) MAPTALDH1A1HPGDLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9728731-B2 Heterocyclic compound and organic light emitting device using same HEESUNG MATERIAL LTD. (KR) 2017-08-08 US disclosed
US-9728731-B2 Heterocyclic compound and organic light emitting device using same HEESUNG MATERIAL LTD. (KR) 2017-08-08 US disclosed
US-20160380208-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME HEESUNG MATERIAL LTD. (KR) 2016-12-29 US disclosed
EP-3088392-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME Heesung Material Ltd. (KR) 2016-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160380208-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME NOTUM, DDT, CRY1 MAPT 1937/4885ALDH1A1 85/4885HPGD 421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.