SCHEMBL18201372

SCHEMBL18201372

CC1(C)c2ccc(Br)cc2-c2cc(I)ccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNB2 O95067 1/20 0.33
CDK1 P06493 1/20 0.33
CCNB1 P14635 1/20 0.33
GSK3B P49841 1/20 0.33
CDK5 Q00535 1/20 0.33
CDK5R1 Q15078 1/20 0.33
CCNB3 Q8WWL7 1/20 0.33
S100A4 P26447 1/20 0.33
TDP2 O95551 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
PDE4B Q07343 1/20 0.32
TGM2 P21980 2/20 0.32
CES1 P23141 2/20 0.32
IDO1 P14902 1/20 0.31
GPR35 Q9HC97 1/20 0.31
CASP3 P42574 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30567840 0.88 S100A4 (0.41) S100A4TDP2CA1CA2CA4
SCHEMBL805016 0.88 S100A4 (0.41) S100A4TDP2CA1CA2CA4
SCHEMBL23332059 0.88 TDP2 (0.38) TDP2TGM2CES1CASP3
SCHEMBL429992 0.81 PDK2 (0.38) CCNB2CDK1CCNB1GSK3BCDK5
SCHEMBL30113034 0.81 PDK2 (0.38) CCNB2CDK1CCNB1GSK3BCDK5
SCHEMBL806937 0.78 PDK2 (0.46) PDE4B
SCHEMBL29564362 0.78 PDK2 (0.46) PDE4B
SCHEMBL19292554 0.78 HTR2A (0.42) TDP2CA1CA2CA4CA7
SCHEMBL13445385 0.78 PDK2 (0.39) TDP2
SCHEMBL19752163 0.78 PDK2 (0.36) S100A4TDP2TGM2CES1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111362811-A A compound of general formula and its application 北京鼎材科技有限公司 2020-07-03 CN disclosed
WO-2016175533-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2016-11-03 WO disclosed