SCHEMBL18201526

SCHEMBL18201526

c1ccc(-c2ccc(Nc3ccc4ccn(-c5ccccc5)c4c3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
HSD17B10 Q99714 2/20 0.42
CYP3A4 P08684 1/20 0.42
HPGD P15428 1/20 0.42
F2 P00734 5/20 0.40
F10 P00742 5/20 0.40
PRSS1 P07477 5/20 0.40
DHODH Q02127 2/20 0.38
HTR6 P50406 1/20 0.38
BIRC5 O15392 1/20 0.38
MEN1 O00255 1/20 0.36
AR P10275 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
PLA2G4A P47712 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15677788 0.80 F2 (0.45) F2F10PRSS1DHODHBIRC5
SCHEMBL17740780 0.80 DHODH (0.51) ALDH1A1HSD17B10CYP3A4HPGDDHODH
SCHEMBL5792785 0.73 BIRC5 (0.67) ALDH1A1HTR6BIRC5MEN1MAPT
SCHEMBL2758570 0.72 BIRC5 (0.61) HTR6BIRC5MEN1KMT2APLA2G4A
SCHEMBL14213823 0.72 HTR6 (0.43) ALDH1A1CYP3A4HTR6BIRC5MAPT
SCHEMBL6846114 0.72 HTR1D (0.48) HTR6MAPT
SCHEMBL14213786 0.72 BIRC5 (0.41) ALDH1A1CYP3A4F2F10PRSS1
SCHEMBL28303496 0.71 PTGER4 (0.37) ALDH1A1HSD17B10MEN1MAPTKMT2A
SCHEMBL22515750 0.71 HTR6 (0.49) DHODHHTR6BIRC5KMT2APLA2G4A
SCHEMBL14188184 0.71 ALDH1A1 (0.80) ALDH1A1HSD17B10CYP3A4HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016175533-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2016-11-03 WO disclosed