Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29882779 | 0.86 | L3MBTL1 (0.44) | L3MBTL1ATMCACNA1GCACNA2D1CACNA1B | |
| SCHEMBL638662 | 0.85 | GABBR2 (0.49) | L3MBTL1ATMCACNA1GCACNA2D1CACNA1B | |
| SCHEMBL10745484 | 0.84 | GABBR2 (0.44) | MEN1KMT2AALDH1A1HTTTSHR | |
| SCHEMBL5670574 | 0.79 | ATM (0.46) | L3MBTL1ATMCACNA1GCACNA2D1CACNA1B | |
| SCHEMBL3382822 | 0.79 | MEN1 (0.44) | L3MBTL1ATMCACNA1GCACNA2D1CACNA1B | |
| SCHEMBL14081313 | 0.79 | CTSA (0.45) | CTSA | |
| SCHEMBL8532074 | 0.79 | TSHR (0.44) | MEN1KMT2AALDH1A1TSHRLMNA | |
| SCHEMBL27644063 | 0.78 | SLC1A3 (0.41) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL5610781 | 0.78 | TDP1 (0.39) | TAS1R3TAS1R1TAS1R2CACNA1GCACNA2D1 | |
| SCHEMBL4987895 | 0.76 | GRM1 (0.36) | TAS1R3TAS1R1TAS1R2CACNA1GCACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928886-B1 | NEW INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | BOEHRINGER INGELHEIM INT (DE) | 2016-11-02 | — | — | EP | disclosed |