⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821278 | 0.84 | IDUA (0.31) | — | |
| SCHEMBL28093271 | 0.84 | IDUA (0.31) | — | |
| SCHEMBL9556151 | 0.82 | — | — | |
| SCHEMBL28641674 | 0.80 | — | — | |
| SCHEMBL4096725 | 0.80 | LGALS3 (0.44) | — | |
| SCHEMBL30353978 | 0.80 | LGALS3 (0.44) | — | |
| SCHEMBL1811839 | 0.80 | LGALS3 (0.44) | — | |
| SCHEMBL7154268 | 0.80 | LGALS3 (0.44) | — | |
| SCHEMBL12085049 | 0.80 | LGALS3 (0.44) | — | |
| SCHEMBL185267 | 0.80 | LGALS3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531681-A | Novel quinoline derivatives for the treatment and prevention of viral infections | ABIVAX公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-103288890-A | Novel method for preparing 3-O-benzyl-1, 2-O-isopropylidene-alpha-L-furan idose | ZHEJIANG HISUN PHARM CO LTD | 2013-09-11 | — | — | CN | disclosed |
| US-20120101052-A9 | 15-THIA STEROID COMPOUNDS AND COMPOSITIONS | BIOVIE INC. | 2012-04-26 | — | — | US | disclosed |
| US-20110218162-A1 | 15-THIA STEROID COMPOUNDS AND COMPOSITIONS | FRINCKE JAMES M | 2011-09-08 | — | — | US | disclosed |
| US-7947846-B2 | 15-OXA-steroid compounds | HARBOR BIOSCIENCES, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| US-20100222425-A1 | COMPOSITIONS AND TREATMENT METHODS-2 | BIOVIE INC. | 2010-09-02 | — | — | US | disclosed |
| EP-2135611-A1 | Pregn-5-en-20-yne-3,7,17-triol derivatives for use in therapy | Hollis-Eden Pharmaceuticals Inc. (US) | 2009-12-23 | — | — | EP | disclosed |
| US-20060079492-A1 | Compositions and treatment methods | BIOVIE INC. | 2006-04-13 | — | — | US | disclosed |
| EP-1372664-A1 | USE OF CERTAIN STEROIDS FOR TREATMENT OF BLOOD CELL DEFICIENCIES | Hollis-Eden Pharmaceuticals Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| US-20030083231-A1 | Blood cell deficiency treatment method | BIOVIE INC. | 2003-05-01 | — | — | US | disclosed |
| WO-2002069977-A1 | USE OF CERTAIN STEROIDS FOR TREATMENT OF BLOOD CELL DEFICIENCIES | HOLLIS-EDEN PHARMACEUTICALS, INC. (US) | 2002-09-12 | — | — | WO | disclosed |