Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.76 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.76 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.76 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.76 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18202375 | 1.00 | GABRA1 (0.76) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| SCHEMBL18202376 | 1.00 | GABRA1 (0.76) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| SCHEMBL28190883 | 0.91 | GABRA1 (0.69) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| SCHEMBL28190884 | 0.91 | GABRA1 (0.69) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| SCHEMBL4390789 | 0.89 | GABRA1 (0.77) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| Propoxate SCHEMBL1817957 | 0.89 | GABRA1 (0.81) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| SCHEMBL28853680 | 0.89 | GABRA1 (0.77) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| SCHEMBL28190853 | 0.89 | GABRA1 (0.69) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| SCHEMBL28190851 | 0.89 | GABRA1 (0.69) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| Hydrochloric Acid SCHEMBL11368079 | 0.88 | GABRA1 (0.58) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9969695-B2 | N-substituted imidazole carboxylic ester chiral compound containing an ether side chain, its preparation and application | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2018-05-15 | — | — | US | disclosed |
| US-9969695-B2 | N-substituted imidazole carboxylic ester chiral compound containing an ether side chain, its preparation and application | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2018-05-15 | — | — | US | disclosed |
| US-20170001963-A1 | N-Substituted Imidazole Carboxylic Ester Chiral Compound Containing an Ether Side Chain, Its Preparation and Application | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2017-01-05 | — | — | US | disclosed |
| US-20170001963-A1 | N-Substituted Imidazole Carboxylic Ester Chiral Compound Containing an Ether Side Chain, Its Preparation and Application | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2017-01-05 | — | — | US | disclosed |
| EP-3088394-A1 | N-SUBSTITUTED IMIDAZOLE CARBOXYLIC ESTER CHIRAL COMPOUND CONTAINING ETHER SIDE CHAIN, PREPARATION METHOD AND APPLICATION | West China Hospital, Sichuan University (CN) | 2016-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170001963-A1 | N-Substituted Imidazole Carboxylic Ester Chiral Compound Containing an Ether Side Chain, Its Preparation and Application | CRH, CYP4A11, CYP3A43 | GABRA1 32/4885GABRB2 146/4885CYP1A2 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.