Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL958642 | 0.71 | — | — | |
| SCHEMBL1886864 | 0.71 | LOX (0.34) | LOXLOXL2 | |
| SCHEMBL4922129 | 0.69 | — | — | |
| SCHEMBL907706 | 0.69 | — | — | |
| SCHEMBL4927705 | 0.69 | — | — | |
| SCHEMBL4885716 | 0.67 | LOX (0.32) | LOXLOXL2 | |
| SCHEMBL3003551 | 0.65 | CA2 (0.34) | LOXLOXL2 | |
| SCHEMBL4882790 | 0.64 | LOX (0.30) | LOXLOXL2 | |
| SCHEMBL4405141 | 0.64 | HPGDS (0.41) | RECQLLOXLOXL2 | |
| SCHEMBL1097322 | 0.64 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011057892-A1 | 2,3-DIHYDROBENZOXAZINE AND 2,3-DIHYDROBENZOTHIAZINE DERIVATES AS HIF-INHIBITORS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASES | ELARA PHARMACEUTICALS GMBH (DE) | 2011-05-19 | — | — | WO | disclosed |