SCHEMBL1820488

SCHEMBL1820488

CCC(C)N(Sc1nc2c(OC)cc(OC)cc2s1)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 2/20 0.39
PDK1 Q15118 1/20 0.33
PPARA Q07869 4/20 0.32
MAPT P10636 2/20 0.31
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1821249 0.89 F2RL3 (0.41) F2RL3PDK1PPARA
SCHEMBL1820930 0.82 F2RL3 (0.41) F2RL3PDK1PPARAMAPTLMNA
SCHEMBL1821957 0.81 F2RL3 (0.39) F2RL3PDK1PPARA
SCHEMBL1821962 0.80 F2RL3 (0.43) F2RL3PDK1PPARAMAPTALDH1A1
SCHEMBL1820157 0.80 F2RL3 (0.40) F2RL3PDK1PPARAMAPTLMNA
SCHEMBL1820704 0.78 F2RL3 (0.39) F2RL3PDK1PPARAMAPTLMNA
SCHEMBL1821538 0.72 ALDH1A1 (0.41) MAPTLMNAMAPK1L3MBTL1ALDH1A1
SCHEMBL8510596 0.72 F2RL3 (0.41) F2RL3PDK1PPARAMAPTLMNA
SCHEMBL8511842 0.72 F2RL3 (0.39) F2RL3PDK1PPARANPC1RAB9A
SCHEMBL8511853 0.72 F2RL3 (0.39) F2RL3PDK1PPARAMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8796387-B2 Rubber composition BRIDGESTONE CORPORATION (JP) 2014-08-05 US disclosed
EP-2316879-B1 RUBBER COMPOSITION BRIDGESTONE CORP (JP) 2013-08-07 EP disclosed
US-20110184109-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-07-28 US disclosed
US-20110172339-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-07-14 US disclosed
US-20110166277-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-07-07 US disclosed
EP-2316881-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2011-05-04 EP disclosed
EP-2316880-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2011-05-04 EP disclosed
EP-2316879-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2011-05-04 EP disclosed