SCHEMBL1820157

SCHEMBL1820157

CCCN(Sc1nc2c(OC)cc(OC)cc2s1)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 2/20 0.40
CRHR1 P34998 11/20 0.35
PDK1 Q15118 1/20 0.34
PPARA Q07869 1/20 0.33
MAPT P10636 2/20 0.32
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1820704 0.93 F2RL3 (0.39) F2RL3CRHR1PDK1PPARAMAPT
SCHEMBL1820930 0.90 F2RL3 (0.41) F2RL3CRHR1PDK1PPARAMAPT
SCHEMBL1821957 0.85 F2RL3 (0.39) F2RL3PDK1PPARA
SCHEMBL1821962 0.81 F2RL3 (0.43) F2RL3PDK1PPARAMAPTALDH1A1
SCHEMBL1820488 0.80 F2RL3 (0.39) F2RL3PDK1PPARAMAPTLMNA
SCHEMBL1821249 0.78 F2RL3 (0.41) F2RL3PDK1PPARA
SCHEMBL8510596 0.73 F2RL3 (0.41) F2RL3PDK1PPARAMAPTLMNA
SCHEMBL8513176 0.73 F2RL3 (0.39) F2RL3PDK1PPARAMAPTLMNA
SCHEMBL1823786 0.72 ALDH1A1 (0.42) MAPTLMNAMAPK1ALDH1A1
SCHEMBL8511734 0.70 F2RL3 (0.40) F2RL3PDK1PPARAMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240317963-A1 RUBBER COMPOSITION FOR HOSE INNER TUBE, LAMINATED BODY, AND HOSE BRIDGESTONE CORPORATION (JP) 2024-09-26 US disclosed
US-20240240001-A1 RUBBER COMPOSITION FOR HOSE INNER TUBE, LAMINATED BODY, AND HOSE BRIDGESTONE CORPORATION (JP) 2024-07-18 US disclosed
EP-4378992-A1 RUBBER COMPOSITION FOR HOSE INNER TUBES, LAMINATE, AND HOSE BRIDGESTONE CORPORATION (JP) 2024-06-05 EP disclosed
EP-4378991-A1 RUBBER COMPOSITION FOR HOSE INNER TUBES, LAMINATE, AND HOSE BRIDGESTONE CORPORATION (JP) 2024-06-05 EP disclosed
EP-2447319-B1 RUBBER CRAWLER BRIDGESTONE CORP (JP) 2017-03-08 EP disclosed
US-8796387-B2 Rubber composition BRIDGESTONE CORPORATION (JP) 2014-08-05 US disclosed
US-8530549-B2 Rubber crawler BRIDGESTONE CORPORATION (JP) 2013-09-10 US disclosed
EP-2316879-B1 RUBBER COMPOSITION BRIDGESTONE CORP (JP) 2013-08-07 EP disclosed
US-20120108738-A1 RUBBER CRAWLER BRIDGESTONE CORPORTATION (JP) 2012-05-03 US disclosed
EP-2447319-A1 RUBBER CRAWLER Bridgestone Corporation (JP) 2012-05-02 EP disclosed
US-20110184109-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-07-28 US disclosed
US-20110172339-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-07-14 US disclosed
US-20110166277-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-07-07 US disclosed
EP-2316881-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2011-05-04 EP disclosed
EP-2316880-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2011-05-04 EP disclosed
EP-2316879-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2011-05-04 EP disclosed