Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Tributylmethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tributylmethylammonium SCHEMBL165919 | 0.97 | SLC22A1 (0.53) | SLC22A1DNM1HTTSLC22A2PLA2G1B | |
| Tributylmethylammonium SCHEMBL10581862 | 0.93 | SLC22A1 (0.50) | SLC22A1DNM1HTTSLC22A2PLA2G1B | |
| Tributylmethylammonium SCHEMBL93610 | 0.93 | SLC22A1 (0.56) | SLC22A1DNM1HTTSLC22A2LSS | |
| Tributylmethylammonium SCHEMBL22190211 | 0.90 | SLC22A1 (0.47) | SLC22A1DNM1HTTSLC22A2PLA2G1B | |
| Hydrochloric Acid SCHEMBL11836905 | 0.90 | DNM1 (0.60) | SLC22A1DNM1HTTSLC22A2LSS | |
| Hydrochloric Acid SCHEMBL11672411 | 0.90 | DNM1 (0.60) | SLC22A1DNM1HTTSLC22A2LSS | |
| Tributylmethylammonium SCHEMBL4617487 | 0.90 | SLC22A1 (0.53) | SLC22A1DNM1HTTSLC22A2LSS | |
| Tributylmethylammonium SCHEMBL3321318 | 0.90 | SLC22A1 (0.53) | SLC22A1DNM1HTTSLC22A2LSS | |
| Tributylmethylammonium SCHEMBL21409548 | 0.90 | SLC22A1 (0.53) | SLC22A1DNM1HTTSLC22A2HSP90AA1 | |
| Tributylmethylammonium SCHEMBL239485 | 0.90 | SLC22A1 (0.53) | SLC22A1DNM1HTTSLC22A2LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2497133-B1 | SOLID-STATE SODIUM-BASED SECONDARY CELL HAVING A SODIUM ION CONDUCTIVE CERAMIC SEPARATOR | FIELD UPGRADING USA INC (US) | 2018-12-26 | — | — | EP | disclosed |
| US-9263770-B2 | Method for providing electrical potential from a sodium-based secondary cell | CERAMATEC, INC. (US) | 2016-02-16 | — | — | US | disclosed |
| US-20140363706-A1 | Method for Providing Electrical Potential from a Sodium-Based Secondary Cell | FIELD UPGRADING USA, INC. | 2014-12-11 | — | — | US | disclosed |
| US-8859141-B2 | Solid-state sodium-based secondary cell having a sodium ion conductive ceramic separator | CERAMATEC, INC. (US) | 2014-10-14 | — | — | US | disclosed |
| EP-2497133-A2 | SOLID-STATE SODIUM-BASED SECONDARY CELL HAVING A SODIUM ION CONDUCTIVE CERAMIC SEPARATOR | Ceramatec, Inc. (US) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011057135-A9 | SOLID-STATE SODIUM-BASED SECONDARY CELL HAVING A SODIUM ION CONDUCTIVE CERAMIC SEPARATOR | CERAMATEC, INC (US) | 2012-06-07 | — | — | WO | disclosed |
| WO-2011057135-A2 | SOLID-STATE SODIUM-BASED SECONDARY CELL HAVING A SODIUM ION CONDUCTIVE CERAMIC SEPARATOR | CERAMATEC, INC (US) | 2011-05-12 | — | — | WO | disclosed |
| US-20110104526-A1 | SOLID-STATE SODIUM-BASED SECONDARY CELL HAVING A SODIUM ION CONDUCTIVE CERAMIC SEPARATOR | FIELD UPGRADING USA, INC. | 2011-05-05 | — | — | US | disclosed |