Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428641 | 0.81 | NPC1 (0.43) | PPARGPPARAPOLBPKMCNR1 | |
| SCHEMBL19415522 | 0.81 | NPC1 (0.43) | PPARGPPARAPOLBPKMCNR1 | |
| SCHEMBL23347648 | 0.80 | NPC1 (0.44) | PPARGPPARAPOLBPKMNPC1 | |
| SCHEMBL19254234 | 0.80 | NPC1 (0.44) | PPARGPPARAPOLBPKMNPC1 | |
| SCHEMBL28652308 | 0.78 | SRR (0.45) | PPARGPPARAPOLBPKMNPC1 | |
| SCHEMBL15082799 | 0.78 | ALDH1A1 (0.46) | PPARGPPARAPOLBPKMNPC1 | |
| SCHEMBL5769266 | 0.74 | PPARG (0.51) | PPARGPPARAPOLBPKMNPC1 | |
| SCHEMBL19415531 | 0.73 | HTT (0.44) | PPARGPPARAPKMNPC1ALDH1A1 | |
| SCHEMBL29168249 | 0.72 | PPARG (0.47) | PPARGPPARAPOLBPKMNPC1 | |
| SCHEMBL29168248 | 0.72 | PPARG (0.47) | PPARGPPARAPOLBPKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2315589-A1 | PHARMACEUTICAL PRODUCT COMPRISING A MUSCARINIC RECEPTOR ANTAGONIST AND A beta2-ADRENOCEPTOR AGONIST | AstraZeneca AB (SE) | 2011-05-04 | — | — | EP | disclosed |