Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | TEK | Q02763 | 2/20 | 0.39 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 4/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1845243 | 0.85 | MAPT (0.49) | CYP19A1PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL1662258 | 0.85 | PIK3CD (0.55) | CYP19A1PIK3CDPIK3CAPIK3CBPI4KA | |
| Hydrochloric Acid SCHEMBL10483927 | 0.84 | MAPT (0.47) | CYP19A1PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL1819377 | 0.83 | MAPT (0.47) | CYP19A1PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL1819910 | 0.83 | CYP19A1 (0.47) | CYP19A1PIK3CDPIK3CAPIK3CBPI4KA | |
| Bromide SCHEMBL12005941 | 0.81 | CYP19A1 (0.46) | CYP19A1PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL17450617 | 0.80 | MAPT (0.51) | CYP19A1PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL30268442 | 0.80 | MAPT (0.51) | CYP19A1PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL8969725 | 0.79 | MAPT (0.54) | CYP19A1PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL7278725 | 0.79 | CYP19A1 (0.64) | CYP19A1PIK3CDPIK3CAPIK3CBPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496571-A2 | PROCESSES FOR THE PREPARATION OF 5-LIPOOXYGENASE ACTIVATING PROTEIN INHIBITORS AND THEIR INTERMEDIATES | Glaxo Group Limited (GB) | 2012-09-12 | — | — | EP | disclosed |
| US-20120220779-A1 | Novel Processes | GLAXO GROUP LIMITED (GB) | 2012-08-30 | — | — | US | disclosed |
| US-20120220779-A1 | Novel Processes | GLAXO GROUP LIMITED (GB) | 2012-08-30 | — | — | US | disclosed |
| US-20120220779-A1 | Novel Processes | GLAXO GROUP LIMITED (GB) | 2012-08-30 | — | — | US | disclosed |
| WO-2011054783-A2 | NOVEL PROCESSES | GLAXO GROUP LIMITED (GB) | 2011-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220779-A1 | Novel Processes | ALOX5, PNPO, ALOX5AP | CYP19A1 727/4885PIK3CD 1536/4885PIK3CA 1097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.