Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720092 | 0.89 | MAPT (0.52) | MAPTRAB9AL3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL16479585 | 0.88 | CASP3 (0.54) | MAPTRAB9AL3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL17795639 | 0.86 | MAPT (0.52) | MAPTRAB9AL3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL8651956 | 0.83 | MAPT (0.47) | MAPTRAB9AL3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL9155978 | 0.82 | MAPT (0.46) | MAPTRAB9AL3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL9159044 | 0.82 | RAB9A (0.46) | MAPTRAB9AL3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL5530443 | 0.82 | RAB9A (0.53) | MAPTRAB9AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL9158713 | 0.81 | MAPT (0.48) | MAPTRAB9AL3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL1662258 | 0.81 | PIK3CD (0.55) | MAPTCYP19A1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL8969875 | 0.81 | MAPT (0.46) | MAPTRAB9AL3MBTL1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445257-B1 | PYRIDINE DERIVATIVES AND A LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 1996-03-13 | — | — | EP | disclosed |
| US-5204477-A | PYRIDINE DERIVATIVES IN LIQUID CRYSTALLINE MEDIUM USEFUL FOR ELECTROOPTICAL DISPLAY ELEMENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-20 | — | — | US | disclosed |
| EP-0445257-A1 | PYRIDINE DERIVATIVES AND A LIQUID CRYSTAL MEDIUM. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |
| WO-1991004249-A1 | PYRIDINE DERIVATIVES AND A LIQUID CRYSTAL MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |