Demannose

Demannose

SCHEMBL18209341

CC(N)=O.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
USP2 O75604 1/20 0.44
SLCO1B1 Q9Y6L6 1/20 0.44
TDP1 Q9NUW8 1/20 0.42
PDE4A P27815 1/20 0.42
KDM4E B2RXH2 2/20 0.38
AKR1B1 P15121 1/20 0.34
PAX8 Q06710 1/20 0.34
ALOX15 P16050 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
TOP1 P11387 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demannose SCHEMBL27656917 1.00 LMNA (0.44) LMNAL3MBTL1USP2SLCO1B1TDP1
Demannose SCHEMBL8425409 0.94 USP2 (0.42) LMNAL3MBTL1USP2SLCO1B1TDP1
Demannose SCHEMBL344073 0.92 LMNA (0.48) LMNAL3MBTL1USP2SLCO1B1TDP1
Demannose SCHEMBL3630269 0.92 PDE4A (0.50) LMNAL3MBTL1USP2SLCO1B1TDP1
Demannose SCHEMBL8560244 0.92 PDE4A (0.50) LMNAL3MBTL1USP2SLCO1B1TDP1
Demannose SCHEMBL23929880 0.92 LMNA (0.48) LMNAL3MBTL1USP2SLCO1B1TDP1
Demannose SCHEMBL2317892 0.92 LMNA (0.48) LMNAL3MBTL1USP2SLCO1B1TDP1
Demannose SCHEMBL8213035 0.92 LMNA (0.48) LMNAL3MBTL1USP2SLCO1B1TDP1
Galactose SCHEMBL7895408 0.92 LMNA (0.48) LMNAL3MBTL1USP2SLCO1B1TDP1
Demannose SCHEMBL25270061 0.92 LMNA (0.48) LMNAL3MBTL1USP2SLCO1B1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110078774-A A kind of non-glucose carbon glycosides dihydrochalcone and preparation method thereof 北京理工亘舒科技有限公司 2019-08-02 CN claimed
CN-110078774-A A kind of non-glucose carbon glycosides dihydrochalcone and preparation method thereof 北京理工亘舒科技有限公司 2019-08-02 CN disclosed
CN-104498420-B It is a kind of produce heparosan recombined bacillus subtilis and its application 江南大学 2019-03-01 CN disclosed
CN-107189992-A A kind of heparosan synthase and its application 江南大学 2017-09-22 CN disclosed
WO-2016178241-A1 A NATURAL ADDITIVE FOR THE STABILISATION OF CONCENTRATED COAL-WATER SLURRY SAMBALPUR UNIVERSITY (IN) 2016-11-10 WO disclosed