SCHEMBL18209591

SCHEMBL18209591

CCCC(C)C(C)(CC)C(N)=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CHRM1 P11229 1/20 0.33
AKR1A1 P14550 1/20 0.33
CHRM3 P20309 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 3/20 0.32
CYP3A4 P08684 2/20 0.32
NFKB1 P19838 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
METAP1 P53582 1/20 0.31
HSD17B10 Q99714 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21673420 0.83 CA1 (0.34) CA1CA2
SCHEMBL1716224 0.81 CHRM1 (0.39) CA2CHRM1AKR1A1CHRM3HTR2A
SCHEMBL19670919 0.79 CA1 (0.36) CA1CA2CHRM1AKR1A1CHRM3
SCHEMBL4886842 0.78 CA2 (0.39) CA1CA2CHRM1AKR1A1CHRM3
SCHEMBL277089 0.78 CA1 (0.32) CA1CA2HSD17B10LMNA
SCHEMBL29127627 0.76 CA1 (0.36) CA1CA2CHRM1AKR1A1CHRM3
SCHEMBL24146801 0.76 CA1 (0.31) CA1CA2
SCHEMBL23906718 0.75 MMP8 (0.41) CA1CA2HTR2ATSHRCYP3A4
SCHEMBL28370308 0.74 CA1 (0.34) CA1CA2
SCHEMBL29169334 0.73 CA1 (0.32) CA1CA2ADRA1ATDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016176743-A1 EMULSIFIABLE CONCENTRATE COMPRISING PICOLINIC ACID HERBICIDE NUFARM AUSTRALIA LIMITED (AU) 2016-11-10 WO claimed