SCHEMBL1821079

SCHEMBL1821079

Brc1c(Br)c(Br)c(B(c2c(Br)c(Br)c(Br)c(Br)c2Br)c2c(Br)c(Br)c(Br)c(Br)c2Br)c(Br)c1Br

nearest known ligand 0.31

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
MAPK1 P28482 1/20 0.31
RECQL P46063 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8852271 0.70
Perbromobenzene SCHEMBL27124 0.67 ALDH1A1 (0.50) CA1CA2CA4CA6ALDH1A1
SCHEMBL8852304 0.67
SCHEMBL22802565 0.67 CA1 (0.35) CA1CA2CA4CA6ALDH1A1
SCHEMBL17061062 0.62
SCHEMBL8852575 0.62
Pentabromophenol SCHEMBL9805044 0.55 CA1 (0.31) CA1CA2CA4CA6ALDH1A1
SCHEMBL2517217 0.55 CA1 (0.31) CA1CA2CA4CA6ALDH1A1
Pentabromophenol SCHEMBL11517668 0.55 CA1 (0.31) CA1CA2CA4CA6ALDH1A1
SCHEMBL11881165 0.53 TSHR (0.44) CA1CA2CA4CA6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7951743-B2 Preparation of ultra high molecular weight linear low density polyethylene EQUISTAR CHEMICALS, LP (US) 2011-05-31 US claimed
US-7429635-B2 Preparation of ultra high molecular weight linear low density polyethylene EQUISTAR CHEMICALS, LP (US) 2008-09-30 US claimed
WO-2008042059-A1 PREPARATION OF ULTRA HIGH MOLECULAR WEIGHT LINEAR LOW DENSITY POLYETHYLENE EQUISTAR CHEMICALS, LP (US) 2008-04-10 WO claimed
US-20080081887-A1 Preparation of ultra high molecular weight linear low density polyethylene EQUISTAR CHEMICALS, LP 2008-04-03 US claimed
US-7094723-B2 Catalysts containing at least one heterocyclic ligand for improving the catalysts' performance of olefin polymerization EQUISTAR CHEMICALS LP (US) 2006-08-22 US claimed
US-6998363-B2 Polyolefin catalyst component using non-covalent interactions THE UNIVERSITY OF HONG KONG (HK) 2006-02-14 US claimed
US-20040248728-A1 Polyolefin catalyst component using non-covalent interactions HONG KONG, UNIVERSITY OF, THE (HK) 2004-12-09 US claimed
WO-2004016627-A1 POLYOLEFIN CATALYST COMPONENT USING NON-COVALENT INTERACTIONS THE UNIVERSITY OF HONG KONG (CN) 2004-02-26 WO claimed
US-20030203807-A1 Catalysts containing at least one heterocyclic ligand for improving the catalysts' performance of olefin polymerization EQUISTAR CHEMICALS L.P. 2003-10-30 US claimed
CN-118055858-B Reinforced polypropylene composition 巴塞尔聚烯烃股份有限公司 2025-04-01 CN disclosed
US-20250011483-A1 REINFORCED POLYPROPYLENE COMPOSITION BASELL POLYOLEFINE GMBH (DE) 2025-01-09 US disclosed
US-12187877-B2 Extrusion additive manufacturing process for producing polyethylene articles BASELL POLYOLEFINE GMBH (DE) 2025-01-07 US disclosed
EP-3927522-B1 EXTRUSION ADDITIVE MANUFACTURING PROCESS FOR PRODUCING POLYETHYLENE ARTICLES BASELL POLYOLEFINE GMBH (DE) 2024-12-11 EP disclosed
CN-118055858-A Reinforced polypropylene composition 巴塞尔聚烯烃股份有限公司 2024-05-17 CN disclosed
US-6180552-B1 OLEFIN POLYMERIZATION COORDINATION CATALYSTS EQUISTAR CHEMICALS, L.P. 2001-01-30 US disclosed
WO-2000059914-A1 METAL COMPOUNDS CONTAINING NEUTRAL, MULTIDENTATE AZACYCLIC LIGANDS, CATALYSTS USING THEM, OLEFIN POLYMERIZATION METHODS USING THEM EQUISTAR CHEMICALS, L.P. (US) 2000-10-12 WO disclosed
US-6127484-A POLYMERIZING AN OLEFIN IN A FIRST ZONE WITH A SINGLE-SITE CATALYST IN THE PRESENCE OF A NON-ALUMOXANE ACTIVATOR TO PRODUCE FIRST POLYMER, TRANSFERRING IT TO A SECOND ZONE WITH ADDITIONAL OLEFIN WITH ZIEGLER NATTA CATALYST ZIEGLER NATTA EQUISTAR CHEMICALS, LP (US) 2000-10-03 US disclosed
US-6020493-A Single-site catalyst preparation EQUISTAR CHEMICALS, LP (US) 2000-02-01 US disclosed
US-5594079-A COORDINATION CATALYST CONTAINING BORON, STEREOREGULAR POLYPROPYLENE TOSOH CORPORATION (JP) 1997-01-14 US disclosed
EP-0582278-A2 Method for producing a polyolefin TOSOH CORPORATION (JP) 1994-02-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030203807-A1 Catalysts containing at least one heterocyclic ligand for improving the catalysts' performance of olefin polymerization NCL, NOXO1, FIS1 CA1 1575/4885CA2 1383/4885CA4 480/4885
US-20040248728-A1 Polyolefin catalyst component using non-covalent interactions TCP1, CCT7, AP1M1 CA1 3696/4885CA2 4726/4885CA4 4016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.