SCHEMBL2517217

SCHEMBL2517217

Brc1c(Br)c(Br)c(Sc2c(Br)c(Br)c(Br)c(Br)c2Br)c(Br)c1Br

nearest known ligand 0.31

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
MAPK1 P28482 1/20 0.31
RECQL P46063 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL259308 0.73 CA1 (0.31) CA1CA2CA4CA6ALDH1A1
Perbromobenzene SCHEMBL27124 0.67 ALDH1A1 (0.50) CA1CA2CA4CA6ALDH1A1
SCHEMBL17364243 0.67
SCHEMBL6568146 0.65
SCHEMBL28443493 0.62 ALDH1A1 (0.36) CA1CA2CA4CA6ALDH1A1
Perbromobenzene SCHEMBL11574212 0.57 ALDH1A1 (0.42) CA1CA2CA4CA6ALDH1A1
SCHEMBL1821079 0.55 CA1 (0.31) CA1CA2CA4CA6ALDH1A1
SCHEMBL6890374 0.55 CA1 (0.31) CA1CA2CA4CA6ALDH1A1
Perbromobenzene SCHEMBL10452958 0.53 CA1 (0.39) CA1CA2CA4CA6ALDH1A1
SCHEMBL11881165 0.53 TSHR (0.44) CA1CA2CA4CA6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020137875-A1 Fire suppressing gas generator composition NAVY, UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF, THE 2002-09-26 US claimed
CN-103641677-A Processing of solid brominated aromatic organic compounds containing occluded bromine ALBEMARLE CORP 2014-03-19 CN disclosed
US-8034986-B2 Heating and agitating concentrated slurry to draw out halogen without decomposition; cooling, precipitating and recovering clean product; low cost purification; flame retardants; recycling elemental and ionic bromine ALBEMARLE CORPORATION (US) 2011-10-11 US disclosed
EP-2079673-A1 PROCESSING OF SOLID BROMINATED AROMATIC ORGANIC COMPOUNDS CONTAINING OCCLUDED BROMINE Albermarle Corporation (US) 2009-07-22 EP disclosed
WO-2008057644-A1 PROCESSING OF SOLID BROMINATED AROMATIC ORGANIC COMPOUNDS CONTAINING OCCLUDED BROMINE ALBEMARLE CORPORATION (US) 2008-05-15 WO disclosed
US-20080114195-A1 PROCESSING OF SOLID BROMINATED AROMATIC ORGANIC COMPOUNDS CONTAINING OCCLUDED BROMINE ALBEMARLE CORPORATION (US) 2008-05-15 US disclosed
EP-1401945-A1 FLAME RETARDANTS AND FLAME RETARDANT COMPOSITIONS FORMED THEREWITH ALBEMARLE CORPORATION (US) 2004-03-31 EP disclosed
US-6558276-B1 Improved feeling without impairing intrinsic resilience; core made from rubber composition of a base rubber, an organic peroxide, an alpha, beta unsaturated carboxylic acid, and a bis type halogen-substituted phenyl disulfide SUMITOMO RUBBER INDUSTRIES LIMITED (JP) 2003-05-06 US disclosed
US-20030030043-A1 Flame retardants and flame retardant compositions formed therewith LANDRY SUSAN D (US) 2003-02-13 US disclosed
US-20030004252-A1 FLAME RETARDANTS AND FLAME RETARDANT COMPOSITIONS FORMED THEREWITH ALBEMARLE CORPORATION 2003-01-02 US disclosed
EP-0018631-B1 THERMALLY STABLE, FLAME-RETARDANT POLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-05-18 EP disclosed
US-4339611-A BUTANOL, BUTANAL, COBALT, IODINE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-07-13 US disclosed
US-4327227-A CATALYZED BROMINATION OF DIPHENYL ETHER GREAT LAKES CHEMICAL CORPORATION (US) 1982-04-27 US disclosed
US-4272429-A POLYAMIDE, OLIGOMER OF AROMATIC DIOL AND BROMINATED DIPHENYL COMPOUND, SYNERGISTIC METAL OXIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-09 US disclosed
US-4254242-A POLYESTER, POLYAMIDE, AROMATIC HALOGEN COMPOUND UNITIKA LTD. (JP) 1981-03-03 US disclosed
EP-0018632-A1 Thermally stable, flame-retardant thermoplastic polyamide resins E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-11-12 EP disclosed
EP-0018631-A1 Thermally stable, flame-retardant polymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-11-12 EP disclosed
US-4220733-A BLEND OF POLYAMIDE WITH SELECTED MODIFIED POLYOLEFINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-09-02 US disclosed
US-4171330-A A BISPHENOL ISOPHTHALATE-TEREPHTHALATE COPOLYESTER BLENDED WITH A LINEAR POLYAMIDE OR POLYLACTAM, A POLYALKYLENE PHENYLENE ESTER OR ESTER ETHER AND AN AROMATIC HALOGEN COMPOUND UNITIKA LTD. (JP) 1979-10-16 US disclosed
US-4144288-A Sodium tetraborate pentahydrate as a smoke suppressant for styrenic resins PENNWALT CORPORATION (US) 1979-03-13 US disclosed