Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLLT1 | Q03111 | 16/20 | 0.51 |
| ▸ | MLLT3 | P42568 | 4/20 | 0.48 |
| ▸ | YEATS2 | Q9ULM3 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813380 | 0.80 | MLLT1 (0.58) | MLLT1MLLT3YEATS2NAMPTDNMT1 | |
| SCHEMBL23432690 | 0.76 | MLLT1 (0.49) | MLLT1MLLT3YEATS2NAMPTDNMT1 | |
| SCHEMBL17790192 | 0.72 | KEAP1 (0.62) | NAMPTMAP3K5 | |
| SCHEMBL16619995 | 0.70 | LOXL2 (0.36) | MAP3K5 | |
| SCHEMBL25124502 | 0.70 | MLLT1 (0.46) | MLLT1MLLT3YEATS2DNMT1 | |
| Hydrochloric Acid SCHEMBL15380752 | 0.70 | MLLT1 (0.49) | MLLT1MLLT3YEATS2NAMPT | |
| SCHEMBL17465971 | 0.67 | MAPK14 (0.46) | — | |
| SCHEMBL24783499 | 0.67 | MLLT1 (0.45) | MLLT1MLLT3YEATS2DNMT1 | |
| SCHEMBL24816112 | 0.66 | DNMT1 (0.46) | MLLT1MLLT3YEATS2NAMPTDNMT1 | |
| SCHEMBL252922 | 0.66 | PIK3CG (0.47) | MLLT1MLLT3DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9486448-B2 | Pyrrolidine derived beta 3 adrenergic receptor agonists | MERCK SHARP & DOHME CORP. (US) | 2016-11-08 | — | — | US | disclosed |
| US-9486448-B2 | Pyrrolidine derived beta 3 adrenergic receptor agonists | MERCK SHARP & DOHME CORP. (US) | 2016-11-08 | — | — | US | disclosed |