Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1823959 | 0.87 | TP53 (0.48) | TP53MAPTMEN1KMT2APOLB | |
| SCHEMBL1616170 | 0.87 | TP53 (0.45) | TP53MAPTCA12CA1CA2 | |
| SCHEMBL1826130 | 0.85 | TP53 (0.44) | TP53MAPTMEN1KMT2APOLB | |
| SCHEMBL1823976 | 0.83 | MEN1 (0.43) | TP53MAPTMEN1KMT2APOLB | |
| SCHEMBL1822442 | 0.82 | TP53 (0.42) | TP53MAPTMEN1KMT2APOLB | |
| SCHEMBL1826315 | 0.82 | TP53 (0.42) | TP53MAPTMEN1KMT2APOLB | |
| SCHEMBL1826145 | 0.82 | TP53 (0.40) | TP53MAPTGRIN1MEN1KMT2A | |
| SCHEMBL1823504 | 0.82 | TP53 (0.49) | TP53MAPTMEN1KMT2APOLB | |
| SCHEMBL1824783 | 0.82 | MAPT (0.44) | TP53MAPTMEN1KMT2APOLB | |
| SCHEMBL1822579 | 0.81 | TP53 (0.41) | TP53MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794122-B1 | 3-SUBSTITUTED-5- AND 6-AMINOALKYL INDOLE-2-CARBOXYLIC ACID AMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I | AVENTIS PHARMA INC (US) | 2011-05-04 | — | — | EP | claimed |