Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824680 | 0.91 | MEN1 (0.54) | TP53HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1823976 | 0.90 | MEN1 (0.43) | TP53MAPTKMT2AMEN1POLB | |
| SCHEMBL1827585 | 0.89 | TP53 (0.53) | TP53KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL1826130 | 0.88 | TP53 (0.44) | TP53KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL1615989 | 0.88 | TP53 (0.56) | TP53KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL1825571 | 0.88 | ALDH1A1 (0.50) | TP53KDM4EHDAC1HDAC8MAPT | |
| SCHEMBL1824216 | 0.87 | TP53 (0.49) | TP53KDM4EHDAC3HDAC1HDAC2 | |
| SCHEMBL1824682 | 0.87 | ALDH1A1 (0.47) | TP53KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL1824783 | 0.87 | MAPT (0.44) | TP53MAPTKMT2AMEN1POLB | |
| SCHEMBL1822868 | 0.86 | TP53 (0.43) | TP53KDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794122-B1 | 3-SUBSTITUTED-5- AND 6-AMINOALKYL INDOLE-2-CARBOXYLIC ACID AMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I | AVENTIS PHARMA INC (US) | 2011-05-04 | — | — | EP | claimed |