Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.38 |
| ▸ | TUBB | P07437 | 3/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1823504 | 0.90 | TP53 (0.49) | MEN1KMT2ATP53MAPTPOLB | |
| SCHEMBL1824783 | 0.89 | MAPT (0.44) | MEN1KMT2ATP53MAPTPOLB | |
| SCHEMBL1826130 | 0.89 | TP53 (0.44) | MEN1KMT2ATP53MAPTPOLB | |
| SCHEMBL1823406 | 0.88 | POLB (0.42) | MEN1KMT2ATP53MAPTPOLB | |
| SCHEMBL1826315 | 0.86 | TP53 (0.42) | MEN1KMT2ATP53MAPTPOLB | |
| SCHEMBL1822442 | 0.86 | TP53 (0.42) | MEN1KMT2ATP53MAPTPOLB | |
| SCHEMBL1827585 | 0.86 | TP53 (0.53) | MEN1KMT2ATP53MAPTPOLB | |
| SCHEMBL1825505 | 0.85 | ALDH1A1 (0.40) | MEN1KMT2ATP53MAPTPOLB | |
| SCHEMBL1823959 | 0.85 | TP53 (0.48) | MEN1KMT2ATP53MAPTPOLB | |
| SCHEMBL1615376 | 0.85 | TP53 (0.46) | MEN1KMT2ATP53MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794122-B1 | 3-SUBSTITUTED-5- AND 6-AMINOALKYL INDOLE-2-CARBOXYLIC ACID AMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I | AVENTIS PHARMA INC (US) | 2011-05-04 | — | — | EP | claimed |