SCHEMBL182132

SCHEMBL182132

Clc1ccc(-n2cccn2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 4/20 1.00
KDM4E B2RXH2 1/20 0.58
ALDH1A1 P00352 1/20 0.58
MAPK1 P28482 1/20 0.58
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
DRD2 P14416 1/20 0.47
DRD4 P21917 1/20 0.47
DRD3 P35462 1/20 0.47
CHRNA7 P36544 1/20 0.45
CHRNA10 Q9GZZ6 1/20 0.45
CHRNA9 Q9UGM1 1/20 0.45
CHRM1 P11229 1/20 0.44
F2 P00734 1/20 0.44
MAPT P10636 2/20 0.43
POLB P06746 1/20 0.43
MAT2A P31153 1/20 0.42
AOC3 Q16853 1/20 0.42
HDAC4 P56524 1/20 0.42
F10 P00742 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4341894 0.89 NOTUM (0.78) NOTUMKDM4EALDH1A1MAPK1MEN1
SCHEMBL4920158 0.82 NOTUM (0.68) NOTUMKDM4EALDH1A1MAPK1MEN1
SCHEMBL173885 0.80 NOTUM (0.67) NOTUMKDM4EALDH1A1MAPK1MEN1
SCHEMBL27250 0.79 NOTUM (0.65) NOTUMKDM4EALDH1A1MAPK1MEN1
SCHEMBL30403096 0.79 NOTUM (0.66) NOTUMKDM4EALDH1A1MAPK1MEN1
SCHEMBL482303 0.78 NOTUM (0.64) NOTUMKDM4EALDH1A1MAPK1MEN1
SCHEMBL8116096 0.78 NOTUM (0.64) NOTUMKDM4EALDH1A1MAPK1MEN1
SCHEMBL674972 0.78 NOTUM (0.64) NOTUMKDM4EALDH1A1MAPK1MEN1
Hydrochloric Acid SCHEMBL7809916 0.78 NOTUM (0.64) NOTUMKDM4EALDH1A1MAPK1MEN1
SCHEMBL82721 0.78 NOTUM (0.64) NOTUMKDM4EALDH1A1MAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118479942-A Production process of green organic fertilizer 山东弘业环保科技有限公司 2024-08-13 CN claimed
CN-118019451-A Fungicidal compositions comprising fludioxonil 先正达农作物保护股份公司 2024-05-10 CN claimed
EP-4346412-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI Industries Ltd. (IN) 2024-04-10 EP claimed
EP-4161264-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2023-04-12 EP claimed
CN-109890794-B Process for purifying 1- (4-chlorophenyl) pyrazol-3-ol 巴斯夫欧洲公司 2023-04-11 CN claimed
WO-2022249074-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2022-12-01 WO claimed
CN-109890794-A The method for purifying 1- (4- chlorphenyl) pyrazoles -3- alcohol 巴斯夫欧洲公司 2019-06-14 CN claimed
CN-106117143-B A kind of preparation method of pyraclostrobin 青岛瀚生生物科技股份有限公司 2019-01-08 CN claimed
EP-0022078-B1 PYRAZOLO-QUINOLINES, PROCESSES FOR THEIR PRODUCTION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1984-07-25 EP claimed
US-20250376452-A1 17-Beta-Hydroxysteroid Dehydrogenase Type 13 Inhibitors and Methods of Use Thereof ENANTA PHARM INC (US) 2025-12-11 US disclosed
EP-4658074-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2025-12-10 EP disclosed
WO-2025242699-A1 METHOD FOR IMPROVING RAINFASTNESS OF AN AGROCHEMICAL ACTIVE INGREDIENT BASF SE (DE) 2025-11-27 WO disclosed
US-20250326713-A1 INHIBITORS OF MsbA AS ANTIBIOTICS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF MERCK SHARP & DOHME LLC (US) 2025-10-23 US disclosed
US-20250312362-A1 INHIBITORS OF MsbA AS ANTIBIOTICS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF MERCK SHARP & DOHME LLC (US) 2025-10-09 US disclosed
US-5985919-A INSECTICIDES AND FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-11-16 US disclosed
EP-0731796-A1 1,3,5-TRISUBSTITUTED PYRAZOLE COMPOUNDS FOR TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1996-09-18 EP disclosed
WO-1995015318-A1 1,3,5-TRISUBSTITUTED PYRAZOLE COMPOUNDS FOR TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1995-06-08 WO disclosed
EP-0022078-B1 PYRAZOLO-QUINOLINES, PROCESSES FOR THEIR PRODUCTION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1984-07-25 EP disclosed
US-4220792-A ANTIDIABETIC AGENTS SANDOZ, INC. (US) 1980-09-02 US disclosed
US-3966755-A OPTICAL BRIGHTENERS CIBA-GEIGY CORPORATION (US) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250376452-A1 17-Beta-Hydroxysteroid Dehydrogenase Type 13 Inhibitors and Methods of Use Thereof HSD17B1, HSD17B13, HSD17B3 NOTUM 440/4885KDM4E 2637/4885ALDH1A1 125/4885
US-20250312362-A1 INHIBITORS OF MsbA AS ANTIBIOTICS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF MSRB3, ABCC1, MRPS34 NOTUM 3456/4885KDM4E 2123/4885ALDH1A1 4233/4885
US-20250326713-A1 INHIBITORS OF MsbA AS ANTIBIOTICS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF MSRB3, ARSA, ABCG2 NOTUM 3145/4885KDM4E 848/4885ALDH1A1 3837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.