Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.69 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.69 |
| ▸ | EDNRA | P25101 | 1/20 | 0.69 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18197026 | 0.93 | LMNA (0.66) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL18197019 | 0.93 | LMNA (0.68) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL28530121 | 0.85 | LMNA (0.80) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL11026728 | 0.84 | LMNA (0.79) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL16518625 | 0.84 | LMNA (0.85) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL11291368 | 0.83 | LMNA (0.76) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL2635855 | 0.82 | LMNA (1.00) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL29384458 | 0.82 | LMNA (1.00) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL33963 | 0.82 | LMNA (1.00) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL11284620 | 0.82 | LMNA (0.75) | LMNACYP2C9ATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160326165-A1 | ALKOXYCARBONYL HEMIACETAL-TYPE ESTER PRODRUG OF PYRIDONE CARBOXYLIC ACID ANTIBACTERIAL DRUG | KINKI UNIVERSITY (JP) | 2016-11-10 | — | — | US | disclosed |
| US-20160326165-A1 | ALKOXYCARBONYL HEMIACETAL-TYPE ESTER PRODRUG OF PYRIDONE CARBOXYLIC ACID ANTIBACTERIAL DRUG | KINKI UNIVERSITY (JP) | 2016-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326165-A1 | ALKOXYCARBONYL HEMIACETAL-TYPE ESTER PRODRUG OF PYRIDONE CARBOXYLIC ACID ANTIBACTERIAL DRUG | ALPI, CYP2B6, CYP2A6 | LMNA 2812/4885CYP2C9 23/4885ATP6V1B2 593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.