Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Enoxacin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 1.00 |
| ▸ | TBXA2R | P21731 | 1/20 | 1.00 |
| ▸ | EDNRA | P25101 | 1/20 | 1.00 |
| ▸ | TARBP2 | Q15633 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | HPGD | P15428 | 6/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | BRD4 | O60885 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Enoxacin SCHEMBL29384458 | 1.00 | LMNA (1.00) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL2635855 | 1.00 | LMNA (1.00) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL11023659 | 0.99 | LMNA (0.98) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL29896709 | 0.99 | LMNA (0.98) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL28451325 | 0.99 | LMNA (0.98) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL29108687 | 0.99 | LMNA (0.98) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL11289413 | 0.99 | LMNA (0.98) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL28065171 | 0.99 | LMNA (0.98) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL11283102 | 0.95 | LMNA (0.91) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL27515554 | 0.94 | LMNA (0.89) | LMNACYP2C9ATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 27161 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122076471-A | Metal basic salt mineralized membrane, preparation method thereof and application of metal basic salt mineralized membrane serving as heterogeneous catalyst in treatment of organic wastewater | — | 2026-05-26 | — | — | CN | claimed |
| US-12624057-B2 | Bisphosphonate quinolone conjugates and uses thereof | BIOVINC, LLC (US) | 2026-05-12 | — | — | US | claimed |
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| US-20260108619-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2026-04-23 | — | — | US | claimed |
| EP-3790536-B1 | NANOCONTAINERS FOR TRANSPORTING NONPOLAR, LIPOPHILIC SUBSTANCES SUCH AS ANTIBIOTICS | KARLSRUHER INST TECHNOLOGIE (DE) | 2026-04-22 | — | — | EP | claimed |
| US-12576124-B2 | Formulation of a conjugate of a tubulysin analog to a cell-binding molecule | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2026-03-17 | — | — | US | claimed |
| US-20260027140-A1 | COMPOSITIONS AND METHODS FOR TREATING AND AMELIORATING RESPIRATORY CONDITIONS AND INFLAMMATION OF MUCOSA | ATOPIC MEDICAL INC (US) | 2026-01-29 | — | — | US | claimed |
| EP-4659014-A1 | EMULSION-BASED THICK-FILM ANTIFOULING COATING FOR HIGHLY SENSITIVE ELECTROCHEMICAL SENSING | President And Fellows Of Harvard College (US) | 2025-12-10 | — | — | EP | claimed |
| US-12465623-B2 | Use of parasites and extracellular vesicles obtained from parasites in cancer treatment | YEDITEPE UNIVERSITESI (TR) | 2025-11-11 | — | — | US | claimed |
| US-20250339551-A1 | AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES | HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) | 2025-11-06 | — | — | US | claimed |
| EP-0067666-B1 | SALTS OF ANTIMICROBIAL NAPHTHYRIDINE AND QUINOLINE COMPOUNDS AND THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1985-10-30 | — | — | EP | claimed |
| EP-0058614-B1 | 1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(1-PIPERAZINYL)-1,8 NAPHTYRIDINE-3-CARBOXYLIC ACID. SESQUIHYDRATE, PROCESSES FOR THE PREPARATION THEREOF AND USE THEREOF AS ANTIBACTERIAL AGENTS | Société anonyme dite: LABORATOIRE ROGER BELLON (FR) | 1985-09-18 | — | — | EP | claimed |
| EP-0130119-A2 | (Acyloxyalkoxy) carbonyl derivatives as bioreversible prodrug moieties for primary and secondary amine functions in drugs, their preparation and pharmaceutical compositions containing said derivatives | MERCK & CO. INC. (US) | 1985-01-02 | — | — | EP | claimed |
| US-4448962-A | BACTERICIDES | KYORIN SEIYAKU KABUSHIKI KAISHA | 1984-05-15 | — | — | US | claimed |
| US-4442101-A | TREATMENT OF BACTERIAL DISEASES | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1984-04-10 | — | — | US | claimed |
| EP-0067666-A1 | Salts of antimicrobial naphthyridine and quinoline compounds and their production | WARNER-LAMBERT COMPANY (US) | 1982-12-22 | — | — | EP | claimed |
| US-4359578-A | Naphthyridine derivatives and salts thereof useful as antibacterial agents | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1982-11-16 | — | — | US | claimed |
| EP-0058614-A1 | 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8 naphtyridine-3-carboxylic acid. Sesquihydrate, processes for the preparation thereof and use thereof as antibacterial agents | Société anonyme dite: LABORATOIRE ROGER BELLON (FR) | 1982-08-25 | — | — | EP | claimed |
| EP-0009425-B1 | NOVEL NAPHTYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Société anonyme dite: LABORATOIRE ROGER BELLON (FR) | 1982-01-27 | — | — | EP | claimed |
| EP-0009425-A1 | Novel naphtyridine derivatives and pharmaceutical compositions containing them | Société anonyme dite: LABORATOIRE ROGER BELLON (FR) | 1980-04-02 | — | — | EP | claimed |