Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28847467 | 0.78 | TYR (0.56) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11334104 | 0.72 | TYR (0.48) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11334099 | 0.72 | TYR (0.48) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11359639 | 0.72 | TYR (0.48) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5268651 | 0.72 | CA12 (0.61) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1822010 | 0.71 | TYR (0.75) | MEN1KMT2ATYRCHRNA7SYNJ2 | |
| SCHEMBL1822012 | 0.71 | TYR (0.75) | MEN1KMT2ATYRCHRNA7SYNJ2 | |
| SCHEMBL675094 | 0.68 | TYR (1.00) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL675095 | 0.68 | TYR (1.00) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11344121 | 0.68 | TYR (0.44) | GAAALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011528336-A | — | — | 2011-11-17 | — | — | JP | claimed |
| EP-2315583-A2 | FORMULATION FOR IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE | Yvery (FR) | 2011-05-04 | — | — | EP | claimed |
| WO-2010007252-A2 | FORMULATION FOR IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE | YVERY (FR) | 2010-01-21 | — | — | WO | claimed |