Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 1.00 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.81 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.70 |
| ▸ | CTSL | P07711 | 1/20 | 0.70 |
| ▸ | CTSB | P07858 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | BACE1 | P56817 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | GMNN | O75496 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675095 | 1.00 | TYR (1.00) | TYRCHRNA7CAPN1CTSLCTSB | |
| SCHEMBL30383155 | 0.91 | TYR (0.82) | TYRCHRNA7CAPN1CTSLCTSB | |
| SCHEMBL29929576 | 0.88 | CHRNA7 (1.00) | TYRCHRNA7CAPN1CTSLCTSB | |
| SCHEMBL2977786 | 0.88 | CHRNA7 (1.00) | TYRCHRNA7CAPN1CTSLCTSB | |
| SCHEMBL322102 | 0.88 | CHRNA7 (1.00) | TYRCHRNA7CAPN1CTSLCTSB | |
| SCHEMBL2977785 | 0.88 | CHRNA7 (1.00) | TYRCHRNA7CAPN1CTSLCTSB | |
| SCHEMBL633742 | 0.88 | CHRNA7 (1.00) | TYRCHRNA7CAPN1CTSLCTSB | |
| SCHEMBL19236264 | 0.88 | CHRNA7 (1.00) | TYRCHRNA7 | |
| SCHEMBL9175439 | 0.87 | TYR (0.77) | TYRCHRNA7CAPN1CTSLCTSB | |
| SCHEMBL9175445 | 0.87 | TYR (0.77) | TYRCHRNA7CAPN1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008172-B | Preparation method and application of effective part with tyrosinase inhibition effect in mulberry twigs | 江南大学 | 2019-06-07 | — | — | CN | claimed |
| CN-106008172-A | Preparation method and application of effective part with tyrosinase inhibition effect in mulberry twigs | 江南大学 | 2016-10-12 | — | — | CN | claimed |
| CN-104886241-A | A browning inhibitor for fresh-cut fruits and vegetables and a preparation method thereof | UNIV JIANGNAN | 2015-09-09 | — | — | CN | claimed |
| JP-11349521-A | — | — | None | — | — | JP | disclosed |
| CN-113180181-A | Browning control method for vacuum-packaged instant lotus root slices | 西南科技大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-106008172-B | Preparation method and application of effective part with tyrosinase inhibition effect in mulberry twigs | 江南大学 | 2019-06-07 | — | — | CN | disclosed |
| CN-106008172-B | Preparation method and application of effective part with tyrosinase inhibition effect in mulberry twigs | 江南大学 | 2019-06-07 | — | — | CN | disclosed |
| US-20190142940-A1 | Method and system for effecting changes in pigmented tissue | MOAZED KAMBIZ THOMAS (US) | 2019-05-16 | — | — | US | disclosed |
| CN-104886241-B | A kind of fresh-cut fruit and vegetable browning inhibitor and preparation method thereof | 江南大学 | 2018-06-08 | — | — | CN | disclosed |
| US-9744237-B2 | Method and system for effecting changes in pigmented tissue | MOAZED KAMBIZ THOMAS (US) | 2017-08-29 | — | — | US | disclosed |
| CN-106008172-A | Preparation method and application of effective part with tyrosinase inhibition effect in mulberry twigs | 江南大学 | 2016-10-12 | — | — | CN | disclosed |
| US-7622563-B2 | Process for producing glycoside | MITSUI CHEMICALS, INC. (JP) | 2009-11-24 | — | — | US | disclosed |
| US-20050272921-A1 | Process for producing glycoside | MITSUI CHEMICALS, INC. (JP) | 2005-12-08 | — | — | US | disclosed |
| EP-1544207-A1 | PROCESS FOR PRODUCING GLYCOSIDE | Mitsui Chemicals, Inc. (JP) | 2005-06-22 | — | — | EP | disclosed |
| US-6737439-B2 | ACTIVE CANCER CHEMOPREVENTATIVE AND TREATING AGENTS IN MAMMALS, INCLUDING HUMANS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2004-05-18 | — | — | US | disclosed |
| US-20030125377-A1 | Aromatase inhibitors from Broussonetia papyrifera | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS THE | 2003-07-03 | — | — | US | disclosed |
| WO-2003013554-A2 | AROMATASE INHIBITORS FROM BROUSSONETIA PAPYRIFERA | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2003-02-20 | — | — | WO | disclosed |
| EP-0522880-B1 | Genetic sequences encoding flavonoid pathway enzymes and uses therefor | INT FLOWER DEV PTY LTD (AU) | 2001-03-21 | — | — | EP | disclosed |
| JP-H11349521-A | NEW CHALCONE COMPOUND AND PHARMACEUTICAL CONTAINING THE COMPOUND | MINOFUAAGEN SEIYAKU:KK | 1999-12-21 | — | — | JP | disclosed |
| EP-0522880-A2 | Genetic sequences encoding flavonoid pathway enzymes and uses therefor | INTERNATIONAL FLOWER DEVELOPMENTS Pty. Ltd. (AU) | 1993-01-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125377-A1 | Aromatase inhibitors from Broussonetia papyrifera | CYP19A1, HSD17B11, CYP17A1 | TYR 947/4885CHRNA7 3805/4885CAPN1 1037/4885 |
| US-20050272921-A1 | Process for producing glycoside | HAAO, OGA, MGAM | TYR 68/4885CHRNA7 2826/4885CAPN1 3896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.