Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943095 | 0.88 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL18214402 | 0.88 | ALDH1A1 (0.40) | ALDH1A1GAAHPGDMAPTKMT2A | |
| SCHEMBL18214409 | 0.85 | SMN1; SMN2 (0.43) | ALDH1A1GAAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL18203192 | 0.85 | ALDH1A1 (0.50) | ALDH1A1GAAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL21980299 | 0.83 | TDP1 (0.42) | ALDH1A1GAASMN1; SMN2MAPTKMT2A | |
| SCHEMBL18214411 | 0.83 | ALDH1A1 (0.39) | ALDH1A1GAAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL18214408 | 0.82 | GAA (0.48) | ALDH1A1GAAMAPTKMT2APOLB | |
| SCHEMBL18214405 | 0.81 | ALDH1A1 (0.42) | ALDH1A1GAAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL20925339 | 0.78 | ALDH1A1 (0.33) | ALDH1A1GAAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL29137837 | 0.76 | ALDH1A1 (0.41) | ALDH1A1GAASMN1; SMN2KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10982071-B2 | Sulfonic acid esters as regulators in radical polymerization reactions | IVOCLAR VIVADENT AG (LI) | 2021-04-20 | — | — | US | disclosed |
| US-10736820-B2 | Materials which can be cured by chain transfer polymerization | IVOCLAR VIVADENT AG (LI) | 2020-08-11 | — | — | US | disclosed |
| EP-3292157-B1 | SULFONIC ACID ESTER AS REGULATOR IN RADICAL POLYMERIZATION REACTIONS | IVOCLAR VIVADENT AG (LI) | 2019-04-24 | — | — | EP | disclosed |
| EP-3090722-B1 | DENTAL MATERIALS WHICH CAN BE HARDENED BY CHAIN-TRANSFER POLYMERIZATION | IVOCLAR VIVADENT AG (LI) | 2019-01-09 | — | — | EP | disclosed |
| US-20180142082-A1 | SULFONIC ACID ESTERS AS REGULATORS IN RADICAL POLYMERIZATION REACTIONS | IVOCLAR VIVADENT AG (LI) | 2018-05-24 | — | — | US | disclosed |
| US-20180142082-A1 | SULFONIC ACID ESTERS AS REGULATORS IN RADICAL POLYMERIZATION REACTIONS | IVOCLAR VIVADENT AG (LI) | 2018-05-24 | — | — | US | disclosed |
| WO-2016177680-A1 | DENTAL MATERIALS THAT CAN BE CURED VIA CHAIN TRANSMISSION POLYMERISATION | IVOCLAR VIVADENT AG (LI) | 2016-11-10 | — | — | WO | disclosed |
| WO-2016177677-A1 | SULFONIC ACID ESTERS AS REGULATORS IN RADICAL POLYMERIZATION REACTIONS | IVOCLAR VIVADENT AG (LI) | 2016-11-10 | — | — | WO | disclosed |
| EP-3091037-A1 | SULFONIC ACID ESTER AS REGULATOR IN RADICAL POLYMERIZATION REACTIONS | Ivoclar Vivadent AG (LI) | 2016-11-09 | — | — | EP | disclosed |
| EP-3090722-A1 | DENTAL MATERIALS WHICH CAN BE HARDENED BY CHAIN-TRANSFER POLYMERIZATION | Ivoclar Vivadent AG (LI) | 2016-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10736820-B2 | Materials which can be cured by chain transfer polymerization | H1-10, CNOT1, C1S | ALDH1A1 1370/4885GAA 2564/4885HPGD 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.