SCHEMBL8943095

SCHEMBL8943095

C=C(OS(=O)(=O)c1ccc(C)cc1)C(=O)OCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
GAA P10253 2/20 0.46
KMT2A Q03164 2/20 0.46
LMNA P02545 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
RECQL P46063 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MAPT P10636 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HTT P42858 1/20 0.42
KDM4E B2RXH2 1/20 0.42
TSHR P16473 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
DHODH Q02127 1/20 0.41
F2 P00734 1/20 0.40
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18214402 0.91 ALDH1A1 (0.40) ALDH1A1GAAKMT2AMAPTNPSR1
SCHEMBL18214403 0.88 ALDH1A1 (0.39) ALDH1A1GAAKMT2ALMNASMN1; SMN2
SCHEMBL18214409 0.88 SMN1; SMN2 (0.43) ALDH1A1GAAKMT2ALMNASMN1; SMN2
SCHEMBL18203192 0.88 ALDH1A1 (0.50) ALDH1A1GAAKMT2ALMNASMN1; SMN2
SCHEMBL29137837 0.87 ALDH1A1 (0.41) ALDH1A1GAAKMT2ALMNASMN1; SMN2
SCHEMBL18214407 0.87 ALDH1A1 (0.44) ALDH1A1GAAKMT2ALMNASMN1; SMN2
SCHEMBL20608735 0.87 ALDH1A1 (0.43) ALDH1A1GAAKMT2ALMNASMN1; SMN2
SCHEMBL21980282 0.87 ALDH1A1 (0.43) ALDH1A1GAAKMT2ALMNASMN1; SMN2
SCHEMBL18214401 0.87 ALDH1A1 (0.43) ALDH1A1GAAKMT2ALMNASMN1; SMN2
SCHEMBL21980299 0.85 TDP1 (0.42) ALDH1A1GAAKMT2ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111228124-B Rapidly curing and low shrinkage stress photopolymerizable dental composites 义获嘉伟瓦登特公司 2024-04-09 CN claimed
US-20230265220-A1 Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress IVOCLAR VIVADENT AG (LI) 2023-08-24 US claimed
US-11673980-B2 Photopolymerizable dental composites with rapid curing and low shrinkage stress IVOCLAR VIVADENT AG (LI) 2023-06-13 US claimed
CN-111228124-A Rapid curing and low shrinkage stress photopolymerizable dental composites 义获嘉伟瓦登特公司 2020-06-05 CN claimed
EP-3659575-A1 PHOTOPOLYMERISABLE DENTAL COMPOSITES WITH FAST CURING AND LOW SHRINKAGE STRESS Ivoclar Vivadent AG (LI) 2020-06-03 EP claimed
US-20200165363-A1 PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS IVOCLAR VIVADENT AG (LI) 2020-05-28 US claimed
US-20250250368-A1 PHOTOCURABLE COMPOSITIONS FOR THREE-DIMENSIONAL INVESTMENT PATTERN CASTING AND USE THEREOF HENKEL AG & CO. KGAA (DE) 2025-08-07 US disclosed
US-20250223460-A1 PHOTOCURABLE COMPOSITIONS FOR ADDITIVE MANUFACTURING AND USE THEREOF HENKEL AG & CO KGAA (DE) 2025-07-10 US disclosed
CN-111228124-B Rapidly curing and low shrinkage stress photopolymerizable dental composites 义获嘉伟瓦登特公司 2024-04-09 CN disclosed
US-20230265220-A1 Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress IVOCLAR VIVADENT AG (LI) 2023-08-24 US disclosed
US-20230265220-A1 Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress IVOCLAR VIVADENT AG (LI) 2023-08-24 US disclosed
US-20230265220-A1 Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress IVOCLAR VIVADENT AG (LI) 2023-08-24 US disclosed
US-11673980-B2 Photopolymerizable dental composites with rapid curing and low shrinkage stress IVOCLAR VIVADENT AG (LI) 2023-06-13 US disclosed
WO-2016177677-A1 SULFONIC ACID ESTERS AS REGULATORS IN RADICAL POLYMERIZATION REACTIONS IVOCLAR VIVADENT AG (LI) 2016-11-10 WO disclosed
EP-3091037-A1 SULFONIC ACID ESTER AS REGULATOR IN RADICAL POLYMERIZATION REACTIONS Ivoclar Vivadent AG (LI) 2016-11-09 EP disclosed
EP-3090722-A1 DENTAL MATERIALS WHICH CAN BE HARDENED BY CHAIN-TRANSFER POLYMERIZATION Ivoclar Vivadent AG (LI) 2016-11-09 EP disclosed
EP-3091037-A1 SULFONIC ACID ESTER AS REGULATOR IN RADICAL POLYMERIZATION REACTIONS Ivoclar Vivadent AG (LI) 2016-11-09 EP disclosed
EP-3090722-A1 DENTAL MATERIALS WHICH CAN BE HARDENED BY CHAIN-TRANSFER POLYMERIZATION Ivoclar Vivadent AG (LI) 2016-11-09 EP disclosed
US-5518877-A POLYPEPTIDE-ADDITION POLYMER AGFA-GEVAERT AG (DE) 1996-05-21 US disclosed
EP-0280556-A2 Water-insoluble particle and immunoreactive reagent, analytical elements and methods of use EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-08-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265220-A1 Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress MMAB, ALAD, SULT1E1 ALDH1A1 355/4885GAA 2821/4885KMT2A 1009/4885
US-11673980-B2 Photopolymerizable dental composites with rapid curing and low shrinkage stress MMAB, ALAD, SULT1E1 ALDH1A1 355/4885GAA 2821/4885KMT2A 1009/4885
US-20200165363-A1 PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS MMAB, ALAD, SULT1E1 ALDH1A1 355/4885GAA 2821/4885KMT2A 1009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.