SCHEMBL18214643

SCHEMBL18214643

CC1C=CC=C(COP(=O)(NCCc2c[nH]c3ccccc23)OC[C@H]2O[C@@](C#N)(c3ccc4c(N)ncnn34)[C@](C)(F)[C@@H]2O)C1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ DCPS Q96C86 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10184151 0.89 DCPS (0.36) DCPS
SCHEMBL14996130 0.89 DCPS (0.36) DCPS
SCHEMBL10183545 0.88 DCPS (0.41) DCPS
SCHEMBL10184144 0.84 DCPS (0.35) DCPS
SCHEMBL12465037 0.81 DCPS (0.35) DCPS
SCHEMBL18214649 0.79 MAPT (0.33) DCPS
SCHEMBL10171882 0.78 DCPS (0.36) DCPS
SCHEMBL882148 0.77 DCPS (0.42) DCPS
SCHEMBL10149577 0.75 MAPT (0.38) —
SCHEMBL18697875 0.75 DCPS (0.42) DCPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2480552-B1 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT GILEAD SCIENCES INC (US) 2016-11-09 — — EP disclosed
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