Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | HINT1 | P49773 | 1/20 | 0.32 |
| ▸ | INMT | O95050 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10183545 | 0.88 | DCPS (0.41) | MAPTABCC1HINT1INMTDCPS | |
| SCHEMBL14996130 | 0.83 | DCPS (0.36) | MAPTABCC1INMTALDH1A1DCPS | |
| SCHEMBL10184151 | 0.83 | DCPS (0.36) | MAPTABCC1INMTALDH1A1DCPS | |
| SCHEMBL10184144 | 0.82 | DCPS (0.35) | MAPTHINT1MEN1KMT2ADCPS | |
| SCHEMBL18214643 | 0.79 | DCPS (0.34) | DCPS | |
| SCHEMBL18214669 | 0.78 | TNK2 (0.32) | — | |
| SCHEMBL10149577 | 0.76 | MAPT (0.38) | MAPTLMNAPOLB | |
| SCHEMBL12465037 | 0.75 | DCPS (0.35) | MAPTABCC1HINT1INMTALDH1A1 | |
| SCHEMBL10149707 | 0.73 | POLRMT (0.38) | — | |
| SCHEMBL18697844 | 0.73 | POLRMT (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2480552-B1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2016-11-09 | — | — | EP | disclosed |