Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.40 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL182152 | 1.00 | PABPC1 (0.47) | PABPC1KMT2APOLBMAPK1CTSS | |
| SCHEMBL180947 | 0.91 | KMT2A (0.47) | PABPC1KMT2APOLBMAPK1CTSS | |
| SCHEMBL180948 | 0.91 | KMT2A (0.47) | PABPC1KMT2APOLBMAPK1CTSS | |
| SCHEMBL182015 | 0.90 | CCKBR (0.43) | KMT2ACALCRL | |
| SCHEMBL181673 | 0.87 | CCKBR (0.38) | PABPC1CALCRL | |
| SCHEMBL181674 | 0.87 | CCKBR (0.38) | PABPC1CALCRL | |
| SCHEMBL181577 | 0.84 | PSMB5 (0.39) | CALCRL | |
| SCHEMBL181578 | 0.84 | PSMB5 (0.39) | CALCRL | |
| SCHEMBL181541 | 0.83 | CCKBR (0.39) | KMT2APOLB | |
| SCHEMBL181542 | 0.83 | CCKBR (0.39) | KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401268-B1 | OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY | RAQUALIA PHARMA INC (JP) | 2015-07-29 | — | — | EP | disclosed |
| EP-2401268-A1 | OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY | RaQualia Pharma Inc (JP) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010098145-A1 | OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY | RAQUALIA PHARMA INC. (JP) | 2010-09-02 | — | — | WO | disclosed |