Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.38 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18215469 | 1.00 | CYP1A2 (0.51) | CYP1A2HSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL18209336 | 1.00 | CYP1A2 (0.51) | CYP1A2HSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL18215417 | 0.81 | HSD17B10 (0.51) | CYP1A2HSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL18209303 | 0.81 | HSD17B10 (0.51) | CYP1A2HSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL18209326 | 0.80 | TDP2 (0.38) | CYP1A2ALDH1A1KDM4EMAPT | |
| SCHEMBL18215457 | 0.80 | TDP2 (0.38) | CYP1A2ALDH1A1KDM4EMAPT | |
| SCHEMBL12917519 | 0.75 | HSD17B10 (0.47) | CYP1A2HSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL18209322 | 0.75 | HSD17B10 (0.49) | CYP1A2HSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL11350887 | 0.75 | HSD17B10 (0.49) | CYP1A2HSD17B10ALDH1A1KDM4EPOLB | |
| SCHEMBL9853855 | 0.73 | CYP1A2 (0.38) | CYP1A2HSD17B10KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016178140-A1 | ISOINDOLINONES, PROCESSES FOR THE PRODUCTION OF CHIRAL DERIVATIVES THEREOF AND USE THEREOF | UNIVERSITA' DEGLI STUDI DI SALERNO (IT) | 2016-11-10 | — | — | WO | disclosed |