SCHEMBL18216985

SCHEMBL18216985

CN(C)c1ccc(C(c2ccc(NCCO)cc2)c2ccc(NCCO)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.46
MAPT P10636 6/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
TSHR P16473 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPK1 P28482 1/20 0.42
PHLPP2 Q6ZVD8 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 6/20 0.41
ADRA2A P08913 2/20 0.41
GAA P10253 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
KMT2A Q03164 3/20 0.39
APP P05067 1/20 0.38
ADRA2B P18089 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4176103 0.89 ADRA2A (0.47) MAPTL3MBTL1TSHRCYP3A4MAPK1
SCHEMBL16689637 0.85 SLC2A1 (0.47) SLC2A1MAPTL3MBTL1TSHRCYP1A2
SCHEMBL5007874 0.82 SLC2A1 (0.45) SLC2A1MAPTL3MBTL1TSHRCYP1A2
SCHEMBL8050759 0.81 MAPT (0.52) MAPTL3MBTL1TSHRCYP1A2CYP3A4
SCHEMBL15537946 0.80 MAPT (0.43) SLC2A1MAPTL3MBTL1TSHRCYP1A2
SCHEMBL5665347 0.78 SLC2A1 (0.41) SLC2A1MAPTL3MBTL1TSHRCYP1A2
SCHEMBL20109506 0.77 SLC2A1 (0.41) SLC2A1MAPTL3MBTL1TSHRCYP1A2
SCHEMBL2759017 0.76 KMT2A (0.59) MAPTTSHRTDP1ALDH1A1GAA
SCHEMBL5010082 0.76 NPC1 (0.51) SLC2A1MAPTL3MBTL1MAPK1ALDH1A1
SCHEMBL61574 0.75 SLC2A1 (0.71) SLC2A1MAPTL3MBTL1TSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11053461-B2 Leuco triphenylmethane colorants as bluing agents in laundry care compositions MILLIKEN & COMPANY (US) 2021-07-06 US disclosed
US-11053460-B2 Leuco triphenylmethane colorants as bluing agents in laundry care compositions MILLIKEN & COMPANY (US) 2021-07-06 US disclosed
US-20200283703-A1 Leuco Triphenylmethane Colorants As Bluing Agents In Laundry Care Compositions MILLIKEN & COMPANY 2020-09-10 US disclosed
US-10723982-B2 Leuco triphenylmethane colorants as bluing agents in laundry care compositions MILLIKEN & COMPANY (US) 2020-07-28 US disclosed
US-9982221-B2 Leuco triphenylmethane colorants as bluing agents in laundry care compositions MILLIKEN & COMPANY (US) 2018-05-29 US disclosed
US-9982221-B2 Leuco triphenylmethane colorants as bluing agents in laundry care compositions MILLIKEN & COMPANY (US) 2018-05-29 US disclosed
US-20180119056-A1 Leuco Triphenylmethane Colorants As Bluing Agents in Laundry Care Compositions MILLIKEN & COMPANY 2018-05-03 US disclosed
US-20180119056-A1 Leuco Triphenylmethane Colorants As Bluing Agents in Laundry Care Compositions MILLIKEN & COMPANY 2018-05-03 US disclosed
WO-2016178668-A9 LEUCO TRIPHENYLMETHANE COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS MILLIKEN & COMPANY (US) 2017-01-05 WO disclosed
WO-2016178668-A1 LEUCO TRIPHENYLMETHANE COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS MILLIKEN & COMPANY (US) 2016-11-10 WO disclosed
US-20160326467-A1 Leuco Triphenylmethane Colorants As Bluing Agents In Laundry Care Compositions MILLIKEN & COMPANY 2016-11-10 US disclosed
US-20160326467-A1 Leuco Triphenylmethane Colorants As Bluing Agents In Laundry Care Compositions MILLIKEN & COMPANY 2016-11-10 US disclosed